A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach
A novel method for the quantitative determination of ranitidine hydrochloride (RNH) based on the fluorescence quenching of functionalised CdS quantum dots (QDs) by RNH in aqueous solution was proposed. The method is simple, rapid, specific and highly sensitive with good precision. The thioglycolic a...
Gespeichert in:
| Veröffentlicht in: | Analyst (London) 2011-06, Vol.136 (12), p.2606-2612 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2612 |
|---|---|
| container_issue | 12 |
| container_start_page | 2606 |
| container_title | Analyst (London) |
| container_volume | 136 |
| creator | Gore, Anil Hanumant Mote, Umesh Shivaji Tele, Shahaji Sopan Anbhule, Prashant Vikramrao Rath, Madhab Chandra Patil, Shivajirao Raghunath Kolekar, Govind Bhagwan |
| description | A novel method for the quantitative determination of ranitidine hydrochloride (RNH) based on the fluorescence quenching of functionalised CdS quantum dots (QDs) by RNH in aqueous solution was proposed. The method is simple, rapid, specific and highly sensitive with good precision. The thioglycolic acid (TGA)-capped CdS QDs were synthesized from cadmium nitrate and sodium sulfide in alkaline solution. Under the optimal conditions, the Stern-Volmer calibration plot of F(0)/F against concentration of RNH was linear in the range of 0.50-15.0 μg mL(-1) with a correlation coefficient of 0.996. The limit of detection (LOD) was 0.38 μg mL(-1). The method was satisfactorily applied to the direct determination of RNH in pharmaceutical formulations with no significant interference from excipients. The results were found to be in good agreement with those obtained by the reference method and the claimed value. The accuracy and reliability of the method were further ascertained by recovery studies via the standard-addition method, with percentage recoveries in the range of 98.47 to 102.30%. The possible fluorescence quenching mechanism for the reaction was also discussed. |
| doi_str_mv | 10.1039/c0an01038c |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_896233456</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>869800573</sourcerecordid><originalsourceid>FETCH-LOGICAL-c348t-cc79e8a4f1725b469eedded13a41f1939fd4704e50c671a728af1d5e0c06f55d3</originalsourceid><addsrcrecordid>eNqFkd2KFDEQhRtR3NnVGx9A6kaEhdakk_SPd8v4Cwsiq9dNplKZjvQkbZIW9h19KDPu6F56lUrqo1LnnKp6xtkrzsTwGpn2rFQ9Pqg2XLSyVqrpH1Ybxpiom1bJs-o8pe_lyplij6uzhis-tE2_qX5dgQ8_aYYD5SkYsCFC1N5lZ5wnmG5NDDjNITpDYChTPDivswsenAf9Y6WwJkhhXv-87XQiA6Ww8xoiJSSPBIXyODm_h2DBrh6PrJ7dkd2aG_jyNkGeYlj3EyxTyMF5s2Jp4qTjniCXjZKlCEtZhlJ6AzcLYY4hYVgcgl5KQ-P0pHpk9Zzo6em8qL69f_d1-7G-_vzh0_bqukYh-1wjdgP1WlreNWon24HIGDJcaMktH8RgjeyYJMWw7bjuml5bbhQxZK1VyoiL6uXd3PJt0ZbyeHBF6jxrf7Rj7Iu3QkjV_p9sh54x1YlCXt6RWGSlSHZcojvoeDtyNh5jHu9jLvDz09h1dyDzD_2bawFenACdUM-2GIgu3XOy6UTHlPgNRp-2cQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>869800573</pqid></control><display><type>article</type><title>A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach</title><source>Royal Society of Chemistry Journals Archive (1841-2007)</source><source>MEDLINE</source><source>Royal Society Of Chemistry Journals 2008-</source><source>Alma/SFX Local Collection</source><creator>Gore, Anil Hanumant ; Mote, Umesh Shivaji ; Tele, Shahaji Sopan ; Anbhule, Prashant Vikramrao ; Rath, Madhab Chandra ; Patil, Shivajirao Raghunath ; Kolekar, Govind Bhagwan</creator><creatorcontrib>Gore, Anil Hanumant ; Mote, Umesh Shivaji ; Tele, Shahaji Sopan ; Anbhule, Prashant Vikramrao ; Rath, Madhab Chandra ; Patil, Shivajirao Raghunath ; Kolekar, Govind Bhagwan</creatorcontrib><description>A novel method for the quantitative determination of ranitidine hydrochloride (RNH) based on the fluorescence quenching of functionalised CdS quantum dots (QDs) by RNH in aqueous solution was proposed. The method is simple, rapid, specific and highly sensitive with good precision. The thioglycolic acid (TGA)-capped CdS QDs were synthesized from cadmium nitrate and sodium sulfide in alkaline solution. Under the optimal conditions, the Stern-Volmer calibration plot of F(0)/F against concentration of RNH was linear in the range of 0.50-15.0 μg mL(-1) with a correlation coefficient of 0.996. The limit of detection (LOD) was 0.38 μg mL(-1). The method was satisfactorily applied to the direct determination of RNH in pharmaceutical formulations with no significant interference from excipients. The results were found to be in good agreement with those obtained by the reference method and the claimed value. The accuracy and reliability of the method were further ascertained by recovery studies via the standard-addition method, with percentage recoveries in the range of 98.47 to 102.30%. The possible fluorescence quenching mechanism for the reaction was also discussed.</description><identifier>ISSN: 0003-2654</identifier><identifier>EISSN: 1364-5528</identifier><identifier>DOI: 10.1039/c0an01038c</identifier><identifier>PMID: 21519628</identifier><identifier>CODEN: ANALAO</identifier><language>eng</language><publisher>Cambridge: Royal Society of Chemistry</publisher><subject>Accuracy ; Analytical chemistry ; Aqueous solutions ; Cadmium Compounds - chemistry ; Cadmium sulfides ; Chemistry ; Exact sciences and technology ; Fluorescence ; Fluorescent Dyes - chemistry ; Hydrochlorides ; Hydrogen-Ion Concentration ; Pharmaceutical Preparations - chemistry ; Quantum Dots ; Quenching ; Ranitidine ; Ranitidine - analysis ; Recovery ; Spectrophotometry, Ultraviolet - methods ; Sulfides - chemistry ; Thioglycolates - chemistry ; Water - chemistry</subject><ispartof>Analyst (London), 2011-06, Vol.136 (12), p.2606-2612</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c348t-cc79e8a4f1725b469eedded13a41f1939fd4704e50c671a728af1d5e0c06f55d3</citedby><cites>FETCH-LOGICAL-c348t-cc79e8a4f1725b469eedded13a41f1939fd4704e50c671a728af1d5e0c06f55d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2818,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24273705$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21519628$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gore, Anil Hanumant</creatorcontrib><creatorcontrib>Mote, Umesh Shivaji</creatorcontrib><creatorcontrib>Tele, Shahaji Sopan</creatorcontrib><creatorcontrib>Anbhule, Prashant Vikramrao</creatorcontrib><creatorcontrib>Rath, Madhab Chandra</creatorcontrib><creatorcontrib>Patil, Shivajirao Raghunath</creatorcontrib><creatorcontrib>Kolekar, Govind Bhagwan</creatorcontrib><title>A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach</title><title>Analyst (London)</title><addtitle>Analyst</addtitle><description>A novel method for the quantitative determination of ranitidine hydrochloride (RNH) based on the fluorescence quenching of functionalised CdS quantum dots (QDs) by RNH in aqueous solution was proposed. The method is simple, rapid, specific and highly sensitive with good precision. The thioglycolic acid (TGA)-capped CdS QDs were synthesized from cadmium nitrate and sodium sulfide in alkaline solution. Under the optimal conditions, the Stern-Volmer calibration plot of F(0)/F against concentration of RNH was linear in the range of 0.50-15.0 μg mL(-1) with a correlation coefficient of 0.996. The limit of detection (LOD) was 0.38 μg mL(-1). The method was satisfactorily applied to the direct determination of RNH in pharmaceutical formulations with no significant interference from excipients. The results were found to be in good agreement with those obtained by the reference method and the claimed value. The accuracy and reliability of the method were further ascertained by recovery studies via the standard-addition method, with percentage recoveries in the range of 98.47 to 102.30%. The possible fluorescence quenching mechanism for the reaction was also discussed.</description><subject>Accuracy</subject><subject>Analytical chemistry</subject><subject>Aqueous solutions</subject><subject>Cadmium Compounds - chemistry</subject><subject>Cadmium sulfides</subject><subject>Chemistry</subject><subject>Exact sciences and technology</subject><subject>Fluorescence</subject><subject>Fluorescent Dyes - chemistry</subject><subject>Hydrochlorides</subject><subject>Hydrogen-Ion Concentration</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Quantum Dots</subject><subject>Quenching</subject><subject>Ranitidine</subject><subject>Ranitidine - analysis</subject><subject>Recovery</subject><subject>Spectrophotometry, Ultraviolet - methods</subject><subject>Sulfides - chemistry</subject><subject>Thioglycolates - chemistry</subject><subject>Water - chemistry</subject><issn>0003-2654</issn><issn>1364-5528</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkd2KFDEQhRtR3NnVGx9A6kaEhdakk_SPd8v4Cwsiq9dNplKZjvQkbZIW9h19KDPu6F56lUrqo1LnnKp6xtkrzsTwGpn2rFQ9Pqg2XLSyVqrpH1Ybxpiom1bJs-o8pe_lyplij6uzhis-tE2_qX5dgQ8_aYYD5SkYsCFC1N5lZ5wnmG5NDDjNITpDYChTPDivswsenAf9Y6WwJkhhXv-87XQiA6Ww8xoiJSSPBIXyODm_h2DBrh6PrJ7dkd2aG_jyNkGeYlj3EyxTyMF5s2Jp4qTjniCXjZKlCEtZhlJ6AzcLYY4hYVgcgl5KQ-P0pHpk9Zzo6em8qL69f_d1-7G-_vzh0_bqukYh-1wjdgP1WlreNWon24HIGDJcaMktH8RgjeyYJMWw7bjuml5bbhQxZK1VyoiL6uXd3PJt0ZbyeHBF6jxrf7Rj7Iu3QkjV_p9sh54x1YlCXt6RWGSlSHZcojvoeDtyNh5jHu9jLvDz09h1dyDzD_2bawFenACdUM-2GIgu3XOy6UTHlPgNRp-2cQ</recordid><startdate>20110621</startdate><enddate>20110621</enddate><creator>Gore, Anil Hanumant</creator><creator>Mote, Umesh Shivaji</creator><creator>Tele, Shahaji Sopan</creator><creator>Anbhule, Prashant Vikramrao</creator><creator>Rath, Madhab Chandra</creator><creator>Patil, Shivajirao Raghunath</creator><creator>Kolekar, Govind Bhagwan</creator><general>Royal Society of Chemistry</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20110621</creationdate><title>A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach</title><author>Gore, Anil Hanumant ; Mote, Umesh Shivaji ; Tele, Shahaji Sopan ; Anbhule, Prashant Vikramrao ; Rath, Madhab Chandra ; Patil, Shivajirao Raghunath ; Kolekar, Govind Bhagwan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c348t-cc79e8a4f1725b469eedded13a41f1939fd4704e50c671a728af1d5e0c06f55d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Accuracy</topic><topic>Analytical chemistry</topic><topic>Aqueous solutions</topic><topic>Cadmium Compounds - chemistry</topic><topic>Cadmium sulfides</topic><topic>Chemistry</topic><topic>Exact sciences and technology</topic><topic>Fluorescence</topic><topic>Fluorescent Dyes - chemistry</topic><topic>Hydrochlorides</topic><topic>Hydrogen-Ion Concentration</topic><topic>Pharmaceutical Preparations - chemistry</topic><topic>Quantum Dots</topic><topic>Quenching</topic><topic>Ranitidine</topic><topic>Ranitidine - analysis</topic><topic>Recovery</topic><topic>Spectrophotometry, Ultraviolet - methods</topic><topic>Sulfides - chemistry</topic><topic>Thioglycolates - chemistry</topic><topic>Water - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gore, Anil Hanumant</creatorcontrib><creatorcontrib>Mote, Umesh Shivaji</creatorcontrib><creatorcontrib>Tele, Shahaji Sopan</creatorcontrib><creatorcontrib>Anbhule, Prashant Vikramrao</creatorcontrib><creatorcontrib>Rath, Madhab Chandra</creatorcontrib><creatorcontrib>Patil, Shivajirao Raghunath</creatorcontrib><creatorcontrib>Kolekar, Govind Bhagwan</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><jtitle>Analyst (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gore, Anil Hanumant</au><au>Mote, Umesh Shivaji</au><au>Tele, Shahaji Sopan</au><au>Anbhule, Prashant Vikramrao</au><au>Rath, Madhab Chandra</au><au>Patil, Shivajirao Raghunath</au><au>Kolekar, Govind Bhagwan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach</atitle><jtitle>Analyst (London)</jtitle><addtitle>Analyst</addtitle><date>2011-06-21</date><risdate>2011</risdate><volume>136</volume><issue>12</issue><spage>2606</spage><epage>2612</epage><pages>2606-2612</pages><issn>0003-2654</issn><eissn>1364-5528</eissn><coden>ANALAO</coden><abstract>A novel method for the quantitative determination of ranitidine hydrochloride (RNH) based on the fluorescence quenching of functionalised CdS quantum dots (QDs) by RNH in aqueous solution was proposed. The method is simple, rapid, specific and highly sensitive with good precision. The thioglycolic acid (TGA)-capped CdS QDs were synthesized from cadmium nitrate and sodium sulfide in alkaline solution. Under the optimal conditions, the Stern-Volmer calibration plot of F(0)/F against concentration of RNH was linear in the range of 0.50-15.0 μg mL(-1) with a correlation coefficient of 0.996. The limit of detection (LOD) was 0.38 μg mL(-1). The method was satisfactorily applied to the direct determination of RNH in pharmaceutical formulations with no significant interference from excipients. The results were found to be in good agreement with those obtained by the reference method and the claimed value. The accuracy and reliability of the method were further ascertained by recovery studies via the standard-addition method, with percentage recoveries in the range of 98.47 to 102.30%. The possible fluorescence quenching mechanism for the reaction was also discussed.</abstract><cop>Cambridge</cop><pub>Royal Society of Chemistry</pub><pmid>21519628</pmid><doi>10.1039/c0an01038c</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2654 |
| ispartof | Analyst (London), 2011-06, Vol.136 (12), p.2606-2612 |
| issn | 0003-2654 1364-5528 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_896233456 |
| source | Royal Society of Chemistry Journals Archive (1841-2007); MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Accuracy Analytical chemistry Aqueous solutions Cadmium Compounds - chemistry Cadmium sulfides Chemistry Exact sciences and technology Fluorescence Fluorescent Dyes - chemistry Hydrochlorides Hydrogen-Ion Concentration Pharmaceutical Preparations - chemistry Quantum Dots Quenching Ranitidine Ranitidine - analysis Recovery Spectrophotometry, Ultraviolet - methods Sulfides - chemistry Thioglycolates - chemistry Water - chemistry |
| title | A novel method for ranitidine hydrochloride determination in aqueous solution based on fluorescence quenching of functionalised CdS QDs through photoinduced charge transfer process: Spectroscopic approach |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T23%3A13%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20novel%20method%20for%20ranitidine%20hydrochloride%20determination%20in%20aqueous%20solution%20based%20on%20fluorescence%20quenching%20of%20functionalised%20CdS%20QDs%20through%20photoinduced%20charge%20transfer%20process:%20Spectroscopic%20approach&rft.jtitle=Analyst%20(London)&rft.au=Gore,%20Anil%20Hanumant&rft.date=2011-06-21&rft.volume=136&rft.issue=12&rft.spage=2606&rft.epage=2612&rft.pages=2606-2612&rft.issn=0003-2654&rft.eissn=1364-5528&rft.coden=ANALAO&rft_id=info:doi/10.1039/c0an01038c&rft_dat=%3Cproquest_cross%3E869800573%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=869800573&rft_id=info:pmid/21519628&rfr_iscdi=true |