Cdc48: a power machine in protein degradation

Cdc48 is an essential, highly prominent ATP driven machine in eukaryotic cells. Physiological function of Cdc48 has been found in a multitude of cellular processes, for instance cell cycle progression, homotypic membrane fusion, chromatin remodeling, transcriptional and metabolic regulation, and man...

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Veröffentlicht in:	Trends in biochemical sciences (Amsterdam. Regular ed.) 2011-10, Vol.36 (10), p.515-523
Hauptverfasser:	Stolz, Alexandra, Hilt, Wolfgang, Buchberger, Alexander, Wolf, Dieter H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - chemistry Adenosine Triphosphatases - metabolism Adenosine Triphosphatases - physiology adenosine triphosphate Autophagy cell cycle Cell Cycle Proteins - chemistry Cell Cycle Proteins - metabolism Cell Cycle Proteins - physiology chromatin Coenzymes - chemistry degradation Endoplasmic Reticulum-Associated Degradation eukaryotic cells Humans membrane fusion Mitochondrial Proteins - metabolism Neurodegenerative Diseases - metabolism Nuclear Proteins - metabolism proteasome endopeptidase complex protein degradation Protein Interaction Domains and Motifs Protein Processing, Post-Translational Protein Structure, Tertiary Proteolysis transcription (genetics) ubiquitin Ubiquitinated Proteins - metabolism Valosin Containing Protein
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