Molecular imaging and depth profiling by mass spectrometry—SIMS, MALDI or DESI?

The possibility of exploiting the analytical power of mass spectrometry to image the chemistry of biological and similarly complex materials without the use of tags and with good spatial resolution is seductive. The status, strengths, weaknesses and complementarity of the three main techniques are b...

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Veröffentlicht in:	Analyst (London) 2011-06, Vol.136 (11), p.2199-2217
1. Verfasser:	VICKERMAN, John C
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Animals Brain - anatomy & histology Chemistry Depth profiling Exact sciences and technology Imaging Male Mass spectrometry Mass Spectrometry - methods Mathematical analysis Molecular Imaging - methods Organic Chemicals - chemistry Prostate - anatomy & histology Proteins - chemistry Proteins - metabolism Spectrometric and optical methods Spectrometry, Mass, Electrospray Ionization - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Spectrometry, Mass, Secondary Ion - methods Spectroscopy Tags
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