Synthesis and anti-microbial activity of hydroxylammonium ionic liquids
[Display omitted] ► We synthesize eight new room temperature ionic liquids (ILs). ► Synthesis is via acid–base neutralization of ethanolamines with organic acids. ► Characterization is via IR and NMR spectroscopies and elemental analysis. ► All eight ILs are toxic to Staphylococcus aureus. ► Two ILs...
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| Veröffentlicht in: | Chemosphere (Oxford) 2011-06, Vol.84 (1), p.101-104 |
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| creator | Ismail Hossain, M. El-Harbawi, Mohanad Noaman, Yousr Abdulhadi Bustam, Mohd Azmi B. Alitheen, Noorjahan Banu Mohamed Affandi, Nor Azrin Hefter, Glenn Yin, Chun-Yang |
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► We synthesize eight new room temperature ionic liquids (ILs). ► Synthesis is via acid–base neutralization of ethanolamines with organic acids. ► Characterization is via IR and NMR spectroscopies and elemental analysis. ► All eight ILs are toxic to Staphylococcus aureus. ► Two ILs show high anti-microbial activity against a wide range of human pathogens.
Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid–base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens. |
| doi_str_mv | 10.1016/j.chemosphere.2011.02.048 |
| format | Article |
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► We synthesize eight new room temperature ionic liquids (ILs). ► Synthesis is via acid–base neutralization of ethanolamines with organic acids. ► Characterization is via IR and NMR spectroscopies and elemental analysis. ► All eight ILs are toxic to Staphylococcus aureus. ► Two ILs show high anti-microbial activity against a wide range of human pathogens.
Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid–base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens.</description><identifier>ISSN: 0045-6535</identifier><identifier>EISSN: 1879-1298</identifier><identifier>DOI: 10.1016/j.chemosphere.2011.02.048</identifier><identifier>PMID: 21421256</identifier><identifier>CODEN: CMSHAF</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Anti-Bacterial Agents - chemical synthesis ; Anti-Bacterial Agents - toxicity ; Anti-microbial screening ; Antibacterial agents ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Biological and medical sciences ; Disinfectants - chemical synthesis ; Disinfectants - toxicity ; Human pathogens ; Hydroxyl ammonium ionic liquids ; Hydroxylamine - chemical synthesis ; Hydroxylamine - toxicity ; Inhibition potential ; Ionic Liquids - chemical synthesis ; Ionic Liquids - toxicity ; Magnetic Resonance Spectroscopy ; Medical sciences ; Pharmacology. Drug treatments ; Spectrophotometry, Infrared ; Staphylococcus aureus ; Staphylococcus aureus - drug effects</subject><ispartof>Chemosphere (Oxford), 2011-06, Vol.84 (1), p.101-104</ispartof><rights>2011</rights><rights>2015 INIST-CNRS</rights><rights>Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c489t-9e40367bec567463f95a9c755491f5e1cbce47ce70f61f6d8ba61edfd228a9db3</citedby><cites>FETCH-LOGICAL-c489t-9e40367bec567463f95a9c755491f5e1cbce47ce70f61f6d8ba61edfd228a9db3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.chemosphere.2011.02.048$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24231943$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21421256$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ismail Hossain, M.</creatorcontrib><creatorcontrib>El-Harbawi, Mohanad</creatorcontrib><creatorcontrib>Noaman, Yousr Abdulhadi</creatorcontrib><creatorcontrib>Bustam, Mohd Azmi B.</creatorcontrib><creatorcontrib>Alitheen, Noorjahan Banu Mohamed</creatorcontrib><creatorcontrib>Affandi, Nor Azrin</creatorcontrib><creatorcontrib>Hefter, Glenn</creatorcontrib><creatorcontrib>Yin, Chun-Yang</creatorcontrib><title>Synthesis and anti-microbial activity of hydroxylammonium ionic liquids</title><title>Chemosphere (Oxford)</title><addtitle>Chemosphere</addtitle><description>[Display omitted]
► We synthesize eight new room temperature ionic liquids (ILs). ► Synthesis is via acid–base neutralization of ethanolamines with organic acids. ► Characterization is via IR and NMR spectroscopies and elemental analysis. ► All eight ILs are toxic to Staphylococcus aureus. ► Two ILs show high anti-microbial activity against a wide range of human pathogens.
Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid–base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens.</description><subject>Anti-Bacterial Agents - chemical synthesis</subject><subject>Anti-Bacterial Agents - toxicity</subject><subject>Anti-microbial screening</subject><subject>Antibacterial agents</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Biological and medical sciences</subject><subject>Disinfectants - chemical synthesis</subject><subject>Disinfectants - toxicity</subject><subject>Human pathogens</subject><subject>Hydroxyl ammonium ionic liquids</subject><subject>Hydroxylamine - chemical synthesis</subject><subject>Hydroxylamine - toxicity</subject><subject>Inhibition potential</subject><subject>Ionic Liquids - chemical synthesis</subject><subject>Ionic Liquids - toxicity</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Spectrophotometry, Infrared</subject><subject>Staphylococcus aureus</subject><subject>Staphylococcus aureus - drug effects</subject><issn>0045-6535</issn><issn>1879-1298</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkE1v1DAQhq2Kii4LfwGFA-KU1HZsJz6iFRSkSj20nC3HHmtnlY-tnVTk39fVboEjh9Fcnnc-HkI-MVoxytT1oXJ7GKZ03EOEilPGKsorKtoLsmFto0vGdfuGbCgVslSyllfkXUoHSnNY6rfkijPBGZdqQ27u13HeQ8JU2NHnmrEc0MWpQ9sX1s34hPNaTKHYrz5Ov9feDsM04jIUmJsrenxc0Kf35DLYPsGHc9-SX9-_Pex-lLd3Nz93X29LJ1o9lxoErVXTgZOqEaoOWlrtGimFZkECc50D0ThoaFAsKN92VjHwwXPeWu27eku-nOYe4_S4QJrNgMlB39sRpiWZVivOapVHb4k-kfmZlCIEc4w42LgaRs2LRnMw_2g0LxoN5SZrzNmP5y1LN4D_k3z1loHPZ8AmZ_sQ7egw_eUEr5kWdeZ2Jw6ykyeEaJJDGB14jOBm4yf8j3OeAQ3qmEI</recordid><startdate>20110601</startdate><enddate>20110601</enddate><creator>Ismail Hossain, M.</creator><creator>El-Harbawi, Mohanad</creator><creator>Noaman, Yousr Abdulhadi</creator><creator>Bustam, Mohd Azmi B.</creator><creator>Alitheen, Noorjahan Banu Mohamed</creator><creator>Affandi, Nor Azrin</creator><creator>Hefter, Glenn</creator><creator>Yin, Chun-Yang</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7ST</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>SOI</scope></search><sort><creationdate>20110601</creationdate><title>Synthesis and anti-microbial activity of hydroxylammonium ionic liquids</title><author>Ismail Hossain, M. ; El-Harbawi, Mohanad ; Noaman, Yousr Abdulhadi ; Bustam, Mohd Azmi B. ; Alitheen, Noorjahan Banu Mohamed ; Affandi, Nor Azrin ; Hefter, Glenn ; Yin, Chun-Yang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c489t-9e40367bec567463f95a9c755491f5e1cbce47ce70f61f6d8ba61edfd228a9db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anti-Bacterial Agents - chemical synthesis</topic><topic>Anti-Bacterial Agents - toxicity</topic><topic>Anti-microbial screening</topic><topic>Antibacterial agents</topic><topic>Antibiotics. Antiinfectious agents. Antiparasitic agents</topic><topic>Biological and medical sciences</topic><topic>Disinfectants - chemical synthesis</topic><topic>Disinfectants - toxicity</topic><topic>Human pathogens</topic><topic>Hydroxyl ammonium ionic liquids</topic><topic>Hydroxylamine - chemical synthesis</topic><topic>Hydroxylamine - toxicity</topic><topic>Inhibition potential</topic><topic>Ionic Liquids - chemical synthesis</topic><topic>Ionic Liquids - toxicity</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Spectrophotometry, Infrared</topic><topic>Staphylococcus aureus</topic><topic>Staphylococcus aureus - drug effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ismail Hossain, M.</creatorcontrib><creatorcontrib>El-Harbawi, Mohanad</creatorcontrib><creatorcontrib>Noaman, Yousr Abdulhadi</creatorcontrib><creatorcontrib>Bustam, Mohd Azmi B.</creatorcontrib><creatorcontrib>Alitheen, Noorjahan Banu Mohamed</creatorcontrib><creatorcontrib>Affandi, Nor Azrin</creatorcontrib><creatorcontrib>Hefter, Glenn</creatorcontrib><creatorcontrib>Yin, Chun-Yang</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Chemosphere (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ismail Hossain, M.</au><au>El-Harbawi, Mohanad</au><au>Noaman, Yousr Abdulhadi</au><au>Bustam, Mohd Azmi B.</au><au>Alitheen, Noorjahan Banu Mohamed</au><au>Affandi, Nor Azrin</au><au>Hefter, Glenn</au><au>Yin, Chun-Yang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis and anti-microbial activity of hydroxylammonium ionic liquids</atitle><jtitle>Chemosphere (Oxford)</jtitle><addtitle>Chemosphere</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>84</volume><issue>1</issue><spage>101</spage><epage>104</epage><pages>101-104</pages><issn>0045-6535</issn><eissn>1879-1298</eissn><coden>CMSHAF</coden><abstract>[Display omitted]
► We synthesize eight new room temperature ionic liquids (ILs). ► Synthesis is via acid–base neutralization of ethanolamines with organic acids. ► Characterization is via IR and NMR spectroscopies and elemental analysis. ► All eight ILs are toxic to Staphylococcus aureus. ► Two ILs show high anti-microbial activity against a wide range of human pathogens.
Eight hydroxylammonium-based room temperature ionic liquids (ILs) have been synthesized by acid–base neutralization of ethanolamines with organic acids. The ILs were characterized by infrared and nuclear magnetic resonance spectroscopies and elemental analysis. Their anti-microbial activities were determined using the well-diffusion method. All eight ILs were toxic to Staphylococcus aureus, while 2-hydroxyethylammonium lactate and 2-hydroxy-N-(2-hydroxyethyl)-N-methylethanaminium acetate showed high anti-microbial activity against a wide range of human pathogens.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>21421256</pmid><doi>10.1016/j.chemosphere.2011.02.048</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - toxicity Anti-microbial screening Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Disinfectants - chemical synthesis Disinfectants - toxicity Human pathogens Hydroxyl ammonium ionic liquids Hydroxylamine - chemical synthesis Hydroxylamine - toxicity Inhibition potential Ionic Liquids - chemical synthesis Ionic Liquids - toxicity Magnetic Resonance Spectroscopy Medical sciences Pharmacology. Drug treatments Spectrophotometry, Infrared Staphylococcus aureus Staphylococcus aureus - drug effects |
| title | Synthesis and anti-microbial activity of hydroxylammonium ionic liquids |
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