Fast in vitro hydrolytic degradation of polyester urethane acrylate biomaterials: Structure elucidation, separation and quantification of degradation products

Synthetic biomaterials have evoked extensive interest for applications in the field of health care. Prior to administration to the body a quantitative study is necessary to evaluate their composition. An in vitro method was developed for the quick hydrolytic degradation of poly-2-hydroxyethyl methac...

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Veröffentlicht in:	Journal of Chromatography A 2011-01, Vol.1218 (3), p.449-458
Hauptverfasser:	Ghaffar, A., Verschuren, P.G., Geenevasen, J.A.J., Handels, T., Berard, J., Plum, B., Dias, A.A., Schoenmakers, P.J., van der Wal, Sj
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylate Biological and medical sciences Biomaterials Biomedical materials Chromatography Chromatography, Gel Chromatography, High Pressure Liquid Degradation Glycolide urethane HPLC–TOF-MS Hydrolysis Hydrolytic degradation Lactic Acid - chemistry Lysine Materials Testing Medical sciences Molecular weight NMR Nuclear Magnetic Resonance, Biomolecular Polyamines - chemistry Polyglycolic Acid - chemistry Polyhydroxyethyl Methacrylate - analogs & derivatives Polyhydroxyethyl Methacrylate - chemistry SEC-dRI Spectrometry, Mass, Electrospray Ionization Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical implants Synthetic polymeric lactide Technology. Biomaterials. Equipments
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