Role of apoptosis in retinoic acid-induced cleft palate

Although the mechanism by which retinoic acid (RA) induces cleft palate has been intensely investigated, some controversies remain. Some researchers argue that RA inhibits apoptosis, resulting in a failure of palatal shelves to fuse, whereas others propose that RA disrupts elevation or retards the g...

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Veröffentlicht in:	The Journal of craniofacial surgery 2011-09, Vol.22 (5), p.1567-1571
Hauptverfasser:	Choi, Jong Woo, Park, Hyung Woo, Kwon, Yoon Jeong, Park, Beyoung Yoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Cleft Palate - chemically induced Cleft Palate - embryology Cleft Palate - pathology Dentistry Disease Models, Animal Female In Situ Nick-End Labeling Pregnancy Rats Rats, Sprague-Dawley Staining and Labeling Tretinoin - toxicity
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