Extent of resection influences outcomes for patients with gliomas

In recent years, advances in our understanding of the biology of low-grade gliomas (LGG) and high-grade gliomas (HGG) have driven new paradigms in molecular markers, diagnostic imaging, operative techniques and technologies, and adjuvant therapies. Taken together, these developments are collectively...

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Veröffentlicht in:Revue neurologique 2011-10, Vol.167 (10), p.648-654
Hauptverfasser: Sanai, N., Berger, M.S.
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description In recent years, advances in our understanding of the biology of low-grade gliomas (LGG) and high-grade gliomas (HGG) have driven new paradigms in molecular markers, diagnostic imaging, operative techniques and technologies, and adjuvant therapies. Taken together, these developments are collectively pushing the envelope towards improved quality of life and survival. Here, we review the recent literature to synthesize a comprehensive review of the value of extent of resection for LGGs and HGGs in the modern neurosurgical era. Les progrès de ces dernières années dans la biologie des gliomes de bas et haut grade de malignité ont conduit à développer de nouveaux paradigmes dans l’imagerie diagnostique, les techniques et technologies opératoires et les traitements adjuvants. Toutes ces avancées contribuent à améliorer la qualité de vie et la survie des patients. Cet article est une revue générale consacrée à la valeur de l’étendue de la résection des gliomes de bas et haut grade à l’ère de la neurochirurgie moderne.
doi_str_mv 10.1016/j.neurol.2011.07.004
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subjects Biological and medical sciences
Biomarkers, Tumor
Brain Neoplasms - pathology
Brain Neoplasms - surgery
Cell Transformation, Neoplastic
Chemoradiotherapy, Adjuvant
Combined Modality Therapy
Extent of resection
Glioma
Glioma - pathology
Glioma - surgery
Gliome
Humans
Magnetic Resonance Imaging
Medical sciences
Microchirurgie
Microsurgical resection
Neural Pathways - pathology
Neurology
Neurosurgical Procedures
Prognosis
Résection chirurgicale
Treatment Outcome
Tumors of the nervous system. Phacomatoses
title Extent of resection influences outcomes for patients with gliomas
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