The role of CD10 in distinguishing atypical fibroxanthoma from sarcomatoid (spindle cell) squamous cell carcinoma

Background: The role of CD10 needs clarification in a broader immunohistochemical battery for distinguishing atypical fibroxanthoma (AFX) from spindle cell squamous cell carcinoma (sSCC). Methods: We retrospectively reviewed 23 cutaneous spindle cell tumors previously classified as AFX (n = 11) or a...

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Veröffentlicht in:	Journal of cutaneous pathology 2011-11, Vol.38 (11), p.884-888
Hauptverfasser:	Wieland, Carilyn N., Dyck, Rayna, Weenig, Roger H., Comfere, Nneka I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomarkers, Tumor - metabolism Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - metabolism cytokeratin Dermatology Diagnosis, Differential differentiation markers Humans Keratins - metabolism Medical sciences Membrane Proteins - metabolism neoplasms Neprilysin - metabolism Retrospective Studies Sarcoma - diagnosis Sarcoma - metabolism Skin Neoplasms - diagnosis Skin Neoplasms - metabolism squamous cell carcinoma Tumors of the skin and soft tissue. Premalignant lesions Xanthomatosis - diagnosis Xanthomatosis - metabolism
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