Combining cytology, TRAP assay, and FISH analysis for the detection of bladder cancer in symptomatic patients

There is a need to improve the performance of urine cytology in bladder cancer diagnosis. We assessed the diagnostic performance of (i) telomerase activity detected by telomeric repeat amplification protocol (TRAP) assay, (ii) cytology and TRAP assay in parallel, (iii) cytology in parallel with the...

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Veröffentlicht in:	Annals of oncology 2011-10, Vol.22 (10), p.2294-2298
Hauptverfasser:	Bravaccini, S., Casadio, V., Gunelli, R., Bucchi, L., Zoli, W., Amadori, D., Silvestrini, R., Calistri, D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic agents Biological and medical sciences bladder cancer Cross-Sectional Studies Cystoscopy cytology diagnosis Female FISH Humans In Situ Hybridization, Fluorescence Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Nucleic Acid Amplification Techniques Pharmacology. Drug treatments Sensitivity and Specificity Telomerase - metabolism telomerase activity Telomere - genetics Tumors of the urinary system Urinary Bladder Neoplasms - diagnosis Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - urine Urinary system involvement in other diseases. Miscellaneous Urinary tract. Prostate gland
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