A Noninvasive [99mTc]DTPA SPECT/CT Imaging Methodology as a Measure of Lung Permeability in a Guinea Pig Model of COPD

Purpose The purposes of this study are (1) to develop an efficient aerosol inhalation system for the delivery of [ 99m Tc]DTPA aerosol into guinea pig airways with high uniformity for measuring lung clearance using SPECT/CT imaging, as a measure of lung permeability, and (2) to use [ 99m Tc]DTPA stu...

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Veröffentlicht in:	Molecular imaging and biology 2011-10, Vol.13 (5), p.923-929
Hauptverfasser:	Wu, Yanjun, Kotzer, Charles J., Makrogiannis, Sokratis, Logan, Gregory A., Haley, Hyking, Barnette, Mary S., Sarkar, Susanta K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Guinea Pigs Imaging Lung - metabolism Medicine Medicine & Public Health Pulmonary Disease, Chronic Obstructive - diagnosis Pulmonary Disease, Chronic Obstructive - diagnostic imaging Pulmonary Disease, Chronic Obstructive - metabolism Radiology Research Article Technetium Tc 99m Pentetate Tomography, Emission-Computed, Single-Photon - methods Tomography, X-Ray Computed - methods
Online-Zugang:	Volltext
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