Probing V5/MT excitability with transcranial magnetic stimulation following visual motion adaptation to random and coherent motion
The response to stimulating the visual cortex with transcranial magnetic stimulation (TMS) depends on its initial activation state, for example, visual motion adaptation biases perceived TMS‐induced phosphene characteristics (e.g., color). We quantified this state dependence by assessing the probabi...
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| Veröffentlicht in: | Annals of the New York Academy of Sciences 2011-09, Vol.1233 (1), p.200-207 |
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| creator | Guzman-Lopez, Jessica Silvanto, Juha Yousif, Nada Nousi, Sofia Quadir, Shamim Seemungal, Barry M. |
| description | The response to stimulating the visual cortex with transcranial magnetic stimulation (TMS) depends on its initial activation state, for example, visual motion adaptation biases perceived TMS‐induced phosphene characteristics (e.g., color). We quantified this state dependence by assessing the probability of reporting a phosphene (Pλ) with “threshold” TMS (i.e., the TMS intensity producing Pλ = 0.5 at baseline) following visual motion adaptation to a random dot motion display. Postadaptation, Pλ was increased, and this effect was confined to the adapted neuronal population. We then adapted subjects using a population of moving dots of fixed average motion direction with standard deviations (SD) ranging from 1° to 128° (SD fixed for a given trial). Pλ was significantly increased at all dot motion SDs except SD = 1°. Neuronal adaptation increases the susceptibility of the neuronal population to activation by threshold intensity TMS. Thus the process of neuronal adaption is not necessarily synonymous with a downmodulation of neuronal excitability. |
| doi_str_mv | 10.1111/j.1749-6632.2011.06179.x |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Activation Adaptation Adaptation, Physiological Adult Color Excitation Female Humans Male motion adaptation Motion Perception - physiology NMR Nuclear magnetic resonance Ocular Physiological Phenomena Phosphene Phosphenes - physiology Photic Stimulation Thresholds Transcranial Magnetic Stimulation V5/MT Visual Visual Cortex - physiology |
| title | Probing V5/MT excitability with transcranial magnetic stimulation following visual motion adaptation to random and coherent motion |
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