ER-α agonist induces conversion of fibroblasts into myofibroblasts, while ER-β agonist increases ECM production and wound tensile strength of healing skin wounds in ovariectomised rats

:  Oestrogen deprivation is one of the major factors responsible for many age‐related processes, including poor wound healing in women. Previously, it has been shown that oestrogens have a modulatory effect in different wound‐healing models. Therefore, in this study, the effect of selective oestroge...

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Veröffentlicht in:Experimental dermatology 2011-09, Vol.20 (9), p.703-708
Hauptverfasser: Novotný, Martin, Vasilenko, Tomáš, Varinská, Lenka, Smetana Jr, Karel, Szabo, Pavol, Šarišský, Marek, Dvořánková, Barbora, Mojžiš, Ján, Bobrov, Nikita, Toporcerová, Silvia, Sabol, Franitšek, Matthews, Bryan J.O., Gál, Peter
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Sprache:eng
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