Influence of heparan sulfate chains in proteoglycan at the dermal-epidermal junction on epidermal homeostasis

: Basement membrane (BM) plays important roles in skin morphogenesis and homeostasis by controlling dermal–epidermal interactions. However, it remains unclear whether heparan sulfate (HS) chains of proteoglycan in epidermal BM contribute to epidermal homeostasis. To explore the function of HS chain...

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Veröffentlicht in:	Experimental dermatology 2011-10, Vol.20 (10), p.810-814
Hauptverfasser:	Iriyama, Shunsuke, Hiruma, Takuya, Tsunenaga, Makoto, Amano, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	basement membrane Biological and medical sciences Dermatology Dermis - anatomy & histology Dermis - drug effects Dermis - metabolism Dermis - radiation effects Enzyme Inhibitors - pharmacology Epidermis - anatomy & histology Epidermis - drug effects Epidermis - metabolism Epidermis - radiation effects Gene Expression - drug effects Glucuronidase - antagonists & inhibitors Heparan Sulfate Proteoglycans - chemistry Heparan Sulfate Proteoglycans - metabolism heparanase Heparitin Sulfate - chemistry Homeostasis - radiation effects Humans keratinocyte Medical sciences Models, Biological perlecan skin equivalent Ultraviolet Rays - adverse effects
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