Magnetic functionalised carbon nanotubes as drug vehicles for cancer lymph node metastasis treatment

Abstract Strategies using carbon-based nanomaterials as carriers for delivering chemotherapeutic drugs to cancers have been described well. Here a novel magnetic lymphatic-targeting drug-delivery system, based on functionalised carbon nanotubes (fCNTs), is presented with the aim of improving the out...

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Veröffentlicht in:	European journal of cancer (1990) 2011-08, Vol.47 (12), p.1873-1882
Hauptverfasser:	Yang, Feng, Jin, Chen, Yang, Dong, Jiang, Yongjian, Li, Ji, Di, Yang, Hu, Jianhua, Wang, Changchun, Ni, Quanxing, Fu, Deliang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antimetabolites, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - pharmacology Apoptosis Biological and medical sciences Biomarkers, Tumor - analysis Cancer Carbon nanotubes Cell Line, Tumor Cell Survival - drug effects Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Deoxycytidine - pharmacology Disease Models, Animal Drug Carriers Gemcitabine Hematology, Oncology and Palliative Medicine Humans Immunohistochemistry In Situ Nick-End Labeling Lymph node metastasis Lymph Nodes - pathology Lymphatic Metastasis Magnetic targeted Magnetite Nanoparticles Medical sciences Mice Mice, Inbred BALB C Mice, Nude Microscopy, Electron, Transmission Nanotubes, Carbon Necrosis Pancreatic Neoplasms - chemistry Pancreatic Neoplasms - drug therapy Pancreatic Neoplasms - pathology Pharmacology. Drug treatments Tumors
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