Recommendations of the American Association of Physicists in Medicine on dosimetry, imaging, and quality assurance procedures for 90Y microsphere brachytherapy in the treatment of hepatic malignancies
Yttrium-90 microsphere brachytherapy of the liver exploits the distinctive features of the liver anatomy to treat liver malignancies with beta radiation and is gaining more wide spread clinical use. This report provides a general overview of microsphere liver brachytherapy and assists the treatment...
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| Veröffentlicht in: | Medical physics (Lancaster) 2011-08, Vol.38 (8), p.4824-4845 |
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| creator | Dezarn, William A. Cessna, Jeffery T. DeWerd, Larry A. Feng, Wenzheng Gates, Vanessa L. Halama, James Kennedy, Andrew S. Nag, Subir Sarfaraz, Mehrdad Sehgal, Varun Selwyn, Reed Stabin, Michael G. Thomadsen, Bruce R. Williams, Lawrence E. Salem, Riad |
| description | Yttrium-90 microsphere brachytherapy of the liver exploits the distinctive features of the liver anatomy to treat liver malignancies with beta radiation and is gaining more wide spread clinical use. This report provides a general overview of microsphere liver brachytherapy and assists the treatment team in creating local treatment practices to provide safe and efficient patient treatment. Suggestions for future improvements are incorporated with the basic rationale for the therapy and currently used procedures. Imaging modalities utilized and their respective quality assurance are discussed. General as well as vendor specific delivery procedures are reviewed. The current dosimetry models are reviewed and suggestions for dosimetry advancement are made. Beta activity standards are reviewed and vendor implementation strategies are discussed. Radioactive material licensing and radiation safety are discussed given the unique requirements of microsphere brachytherapy. A general, team-based quality assurance program is reviewed to provide guidance for the creation of the local procedures. Finally, recommendations are given on how to deliver the current state of the art treatments and directions for future improvements in the therapy. |
| doi_str_mv | 10.1118/1.3608909 |
| format | Article |
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Cessna, Jeffery T. ; DeWerd, Larry A. ; Feng, Wenzheng ; Gates, Vanessa L. ; Halama, James ; Kennedy, Andrew S. ; Nag, Subir ; Sarfaraz, Mehrdad ; Sehgal, Varun ; Selwyn, Reed ; Stabin, Michael G. ; Thomadsen, Bruce R. ; Williams, Lawrence E. ; Salem, Riad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1989-11857718ff7c9df2152b48a9ed3055a62fea0c11a85fa148b27d505462165ec63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anatomy</topic><topic>Angiography - standards</topic><topic>biomedical MRI</topic><topic>brachytherapy</topic><topic>Brachytherapy - standards</topic><topic>Calibration</topic><topic>Cancer</topic><topic>Computed tomography</topic><topic>computerised tomography</topic><topic>dosimetry</topic><topic>Dosimetry/exposure assessment</topic><topic>Health Physics</topic><topic>Humans</topic><topic>Image Interpretation, Computer-Assisted - standards</topic><topic>imaging</topic><topic>liver</topic><topic>Liver Neoplasms - diagnostic imaging</topic><topic>Liver Neoplasms - pathology</topic><topic>Liver Neoplasms - radiotherapy</topic><topic>Lungs</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical imaging</topic><topic>microsphere</topic><topic>Microspheres</topic><topic>Positron-Emission Tomography</topic><topic>Quality Assurance, Health Care - standards</topic><topic>radioembolization</topic><topic>Radiometry - standards</topic><topic>Single photon emission computed tomography</topic><topic>Societies, Medical</topic><topic>Therapeutic applications, including brachytherapy</topic><topic>Tomography, X-Ray Computed</topic><topic>United States</topic><topic>yttrium</topic><topic>Yttrium Radioisotopes - standards</topic><topic>Yttrium Radioisotopes - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dezarn, William A.</creatorcontrib><creatorcontrib>Cessna, Jeffery T.</creatorcontrib><creatorcontrib>DeWerd, Larry A.</creatorcontrib><creatorcontrib>Feng, Wenzheng</creatorcontrib><creatorcontrib>Gates, Vanessa L.</creatorcontrib><creatorcontrib>Halama, James</creatorcontrib><creatorcontrib>Kennedy, Andrew S.</creatorcontrib><creatorcontrib>Nag, Subir</creatorcontrib><creatorcontrib>Sarfaraz, Mehrdad</creatorcontrib><creatorcontrib>Sehgal, Varun</creatorcontrib><creatorcontrib>Selwyn, Reed</creatorcontrib><creatorcontrib>Stabin, Michael G.</creatorcontrib><creatorcontrib>Thomadsen, Bruce R.</creatorcontrib><creatorcontrib>Williams, Lawrence E.</creatorcontrib><creatorcontrib>Salem, Riad</creatorcontrib><creatorcontrib>American Association of Physicists in Medicine</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dezarn, William A.</au><au>Cessna, Jeffery T.</au><au>DeWerd, Larry A.</au><au>Feng, Wenzheng</au><au>Gates, Vanessa L.</au><au>Halama, James</au><au>Kennedy, Andrew S.</au><au>Nag, Subir</au><au>Sarfaraz, Mehrdad</au><au>Sehgal, Varun</au><au>Selwyn, Reed</au><au>Stabin, Michael G.</au><au>Thomadsen, Bruce R.</au><au>Williams, Lawrence E.</au><au>Salem, Riad</au><aucorp>American Association of Physicists in Medicine</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recommendations of the American Association of Physicists in Medicine on dosimetry, imaging, and quality assurance procedures for 90Y microsphere brachytherapy in the treatment of hepatic malignancies</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2011-08</date><risdate>2011</risdate><volume>38</volume><issue>8</issue><spage>4824</spage><epage>4845</epage><pages>4824-4845</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>Yttrium-90 microsphere brachytherapy of the liver exploits the distinctive features of the liver anatomy to treat liver malignancies with beta radiation and is gaining more wide spread clinical use. This report provides a general overview of microsphere liver brachytherapy and assists the treatment team in creating local treatment practices to provide safe and efficient patient treatment. Suggestions for future improvements are incorporated with the basic rationale for the therapy and currently used procedures. Imaging modalities utilized and their respective quality assurance are discussed. General as well as vendor specific delivery procedures are reviewed. The current dosimetry models are reviewed and suggestions for dosimetry advancement are made. Beta activity standards are reviewed and vendor implementation strategies are discussed. Radioactive material licensing and radiation safety are discussed given the unique requirements of microsphere brachytherapy. A general, team-based quality assurance program is reviewed to provide guidance for the creation of the local procedures. Finally, recommendations are given on how to deliver the current state of the art treatments and directions for future improvements in the therapy.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>21928655</pmid><doi>10.1118/1.3608909</doi><tpages>22</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Anatomy Angiography - standards biomedical MRI brachytherapy Brachytherapy - standards Calibration Cancer Computed tomography computerised tomography dosimetry Dosimetry/exposure assessment Health Physics Humans Image Interpretation, Computer-Assisted - standards imaging liver Liver Neoplasms - diagnostic imaging Liver Neoplasms - pathology Liver Neoplasms - radiotherapy Lungs Magnetic Resonance Imaging Medical imaging microsphere Microspheres Positron-Emission Tomography Quality Assurance, Health Care - standards radioembolization Radiometry - standards Single photon emission computed tomography Societies, Medical Therapeutic applications, including brachytherapy Tomography, X-Ray Computed United States yttrium Yttrium Radioisotopes - standards Yttrium Radioisotopes - therapeutic use |
| title | Recommendations of the American Association of Physicists in Medicine on dosimetry, imaging, and quality assurance procedures for 90Y microsphere brachytherapy in the treatment of hepatic malignancies |
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