Upregulation of Rac GTPase-Activating Protein 1 Is Significantly Associated with the Early Recurrence of Human Hepatocellular Carcinoma

To assess the significance of Rac GTPase-activating protein 1 (RACGAP1) expression in identifying HBV-positive human hepatocellular carcinoma (HCC) patients who are at high risk for recurrent disease. The prognostic significance of RACGAP1 was compared with clinicopathologic parameters available at...

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Veröffentlicht in:	Clinical cancer research 2011-09, Vol.17 (18), p.6040-6051
Hauptverfasser:	WANG, Suk Mei, OOI, London Lucien P. J, HUI, Kam M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Carcinoma, Hepatocellular - diagnosis Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - mortality Cell Line, Tumor Cell Movement - genetics Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Gene Silencing GTPase-Activating Proteins - genetics GTPase-Activating Proteins - metabolism Hep G2 Cells Humans Kaplan-Meier Estimate Liver Neoplasms - diagnosis Liver Neoplasms - genetics Liver Neoplasms - metabolism Liver Neoplasms - mortality Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Neoplasm Recurrence, Local - diagnosis Pharmacology. Drug treatments Prognosis rac1 GTP-Binding Protein Recurrence RNA, Small Interfering Signal Transduction Tumors Up-Regulation - genetics
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