Hepatic Differentiation from Human Embryonic Stem Cells Using Stromal Cells

Objective The derivation of hepatocytes from human embryonic stem (hES) cells is of value both in the study of early human liver organogenesis and in the creation of an unlimited source of donor cells for hepatocyte transplantation therapy. Here, we report the generation of hepatocyte-like cells der...

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Veröffentlicht in:	The Journal of surgical research 2011-10, Vol.170 (2), p.e253-e261
Hauptverfasser:	Yu, Young-Dong, M.D., Ph.D, Kim, Ki-Hun, M.D., Ph.D, Lee, Sung-Gyu, M.D., Ph.D, Choi, Sang-Yong, M.D., Ph.D, Kim, Young-Chul, M.D., Ph.D, Byun, Kwan-Su, M.D., Ph.D, Cha, In-Ho, M.D., Ph.D, Park, Kye-Yoon, Ph.D, Cho, Cheul-Hyung, Ph.D, Choi, Dong-Ho, M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Animals Biomarkers - metabolism Cell Culture Techniques - methods Cell Differentiation - physiology Cell Division - physiology Cells, Cultured Coculture Techniques Embryoid Bodies - physiology Embryonic Stem Cells - cytology Endoderm - cytology Green Fluorescent Proteins - genetics hepatocytes Hepatocytes - cytology human embryonic stem cells Humans Mice Mitomycin - pharmacology Nucleic Acid Synthesis Inhibitors - pharmacology stromal cells Stromal Cells - cytology Stromal Cells - drug effects Surgery
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