Effect of high-dose phenobarbital on oxidative stress in perinatal asphyxia: An open label randomized controlled trial

Objective To evaluate the effect of high dose phenobarbital on lipid peroxidation and antioxidant enzymes in perinatal asphyxia. Design Open label, Randomized controlled trial. Setting Neonatal intensive care unit of a tertiary care teaching hospital. Participants 72 full term inborn neonates with s...

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Veröffentlicht in:	Indian pediatrics 2011-08, Vol.48 (8), p.613-617
Hauptverfasser:	Gathwala, Geeta, Marwah, Ashish, Gahlaut, Veena, Marwah, Poonam
Format:	Artikel
Sprache:	eng
Schlagworte:	Asphyxia Neonatorum - cerebrospinal fluid Asphyxia Neonatorum - drug therapy Asphyxia Neonatorum - metabolism Glutathione Peroxidase - cerebrospinal fluid Hospitals, Teaching Humans Hypoxia-Ischemia, Brain - cerebrospinal fluid Hypoxia-Ischemia, Brain - drug therapy Hypoxia-Ischemia, Brain - metabolism Infant, Newborn Intensive Care Units, Neonatal Lipid Peroxidation - drug effects Malondialdehyde - cerebrospinal fluid Maternal and Child Health Medicine Medicine & Public Health Neuroprotective Agents - administration & dosage Oxidative Stress - drug effects Pediatric Surgery Pediatrics Phenobarbital - administration & dosage Research Paper Superoxide Dismutase - cerebrospinal fluid
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