Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning

► Thirteen cDNAs of dermal peptides were identified in the frog Odorana ishikawae. ► Five peptides were new members of known antimicrobial peptides families in the frogs. ► Eight peptides were novel dermal peptides which have not been identified previously. ► Antimicrobial activities of the novel de...

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Veröffentlicht in:	Biochemical and biophysical research communications 2011-09, Vol.412 (4), p.673-677
Hauptverfasser:	Iwakoshi-Ukena, Eiko, Soga, Miyuki, Okada, Genya, Fujii, Tamotsu, Sumida, Masayuki, Ukena, Kazuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Antimicrobial Cationic Peptides - genetics Antimicrobial Cationic Peptides - pharmacology Antimicrobial peptide Anura Cloning, Molecular DNA, Complementary - genetics Endangered Species Escherichia coli - drug effects Frog skin Fungi - drug effects Gram-Positive Bacteria - drug effects Innate immunity Microbial Sensitivity Tests Microorganism Molecular Sequence Data Odorrana Ranidae - genetics Ranidae - immunology Ranidae - microbiology Skin - immunology Skin - microbiology
Online-Zugang:	Volltext
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