A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: A combination of Martínez-Gimeno Scoring System and clinical palpation
Abstract Aims Evaluation of the accuracy of palpation, CT scan and Martínez-Gimeno Score System in the assessment of neck nodes metastasis in squamous cell carcinoma of the oral cavity. Design This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma...
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| Veröffentlicht in: | Journal of cranio-maxillo-facial surgery 2011-10, Vol.39 (7), p.534-537 |
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| container_title | Journal of cranio-maxillo-facial surgery |
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| creator | Martínez-Gimeno, Carlos Rodríguez-Delgado, Luisa Elena Perera-Molinero, Antonio Trujillo, María del Carmen Chivite, Ana Maeso, Maria Carmen Aguirre-Jaime, Armando |
| description | Abstract Aims Evaluation of the accuracy of palpation, CT scan and Martínez-Gimeno Score System in the assessment of neck nodes metastasis in squamous cell carcinoma of the oral cavity. Design This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma of the oral cavity. Patients: 40 consecutive patients suffering primary oral squamous cell carcinoma, without any treatment before surgery, palpation or CT Scan. Results 40% of the cases showed metastasis in pathological study. Sensitivity was 100%, 94% and 75% for MGSS 13, CT scan and palpation, respectively. Specificity was 83%, 38% and 25–50% for palpation, CT scan and MGSS 13–17, respectively. Negative predictive result values were 100%, 90% and 83% for MGSS 13, CT Scan and palpation. The logistic regression analysis showed an independent predictor factor for palpation ( p = 0.001) and MGSS ( p = 0.01). The combination of MGSS and clinical palpation allowed a new design for evaluating neck metastasis in oral cancer. This method establishes 3 different groups at risk: 3 of very low ( |
| doi_str_mv | 10.1016/j.jcms.2010.10.027 |
| format | Article |
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Design This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma of the oral cavity. Patients: 40 consecutive patients suffering primary oral squamous cell carcinoma, without any treatment before surgery, palpation or CT Scan. Results 40% of the cases showed metastasis in pathological study. Sensitivity was 100%, 94% and 75% for MGSS 13, CT scan and palpation, respectively. Specificity was 83%, 38% and 25–50% for palpation, CT scan and MGSS 13–17, respectively. Negative predictive result values were 100%, 90% and 83% for MGSS 13, CT Scan and palpation. The logistic regression analysis showed an independent predictor factor for palpation ( p = 0.001) and MGSS ( p = 0.01). The combination of MGSS and clinical palpation allowed a new design for evaluating neck metastasis in oral cancer. This method establishes 3 different groups at risk: 3 of very low (<2%), 2 of low risk (18–27%) and 1 of high risk (85%). Conclusions MGSS predicts metastasis better than CT scan and palpation. Combination of MGSS and palpation improves the prediction of metastasis.</description><identifier>ISSN: 1010-5182</identifier><identifier>EISSN: 1878-4119</identifier><identifier>DOI: 10.1016/j.jcms.2010.10.027</identifier><identifier>PMID: 21112791</identifier><identifier>CODEN: JCMSET</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Carcinoma, Squamous Cell - pathology ; Carcinoma, Squamous Cell - secondary ; Clinical palpation ; Computerized tomography ; Dentistry ; Dermatology ; Double-Blind Method ; Female ; Head and neck metastasis ; Hematologic and hematopoietic diseases ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Logistic Models ; Lymph Nodes - diagnostic imaging ; Lymph Nodes - pathology ; Lymphatic Metastasis - diagnosis ; Male ; Martínez-Gimeno Scoring System ; Medical sciences ; Middle Aged ; Mouth Neoplasms - pathology ; Neck ; Neck Dissection - utilization ; Neoplasm Grading - methods ; Oral cancer ; Otorhinolaryngology. Stomatology ; Palpation ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Assessment ; Squamous cell carcinoma ; Surgery ; Tomography, X-Ray Computed ; Tumors ; Tumors of the skin and soft tissue. Premalignant lesions ; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><ispartof>Journal of cranio-maxillo-facial surgery, 2011-10, Vol.39 (7), p.534-537</ispartof><rights>European Association for Cranio-Maxillo-Facial Surgery</rights><rights>2010 European Association for Cranio-Maxillo-Facial Surgery</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-63b799a29df12f7220a1ef9023fa2319db1d77edf17c65c7e9834051a9541ef73</citedby><cites>FETCH-LOGICAL-c440t-63b799a29df12f7220a1ef9023fa2319db1d77edf17c65c7e9834051a9541ef73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jcms.2010.10.027$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24562976$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21112791$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Martínez-Gimeno, Carlos</creatorcontrib><creatorcontrib>Rodríguez-Delgado, Luisa Elena</creatorcontrib><creatorcontrib>Perera-Molinero, Antonio</creatorcontrib><creatorcontrib>Trujillo, María del Carmen</creatorcontrib><creatorcontrib>Chivite, Ana</creatorcontrib><creatorcontrib>Maeso, Maria Carmen</creatorcontrib><creatorcontrib>Aguirre-Jaime, Armando</creatorcontrib><title>A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: A combination of Martínez-Gimeno Scoring System and clinical palpation</title><title>Journal of cranio-maxillo-facial surgery</title><addtitle>J Craniomaxillofac Surg</addtitle><description>Abstract Aims Evaluation of the accuracy of palpation, CT scan and Martínez-Gimeno Score System in the assessment of neck nodes metastasis in squamous cell carcinoma of the oral cavity. Design This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma of the oral cavity. Patients: 40 consecutive patients suffering primary oral squamous cell carcinoma, without any treatment before surgery, palpation or CT Scan. Results 40% of the cases showed metastasis in pathological study. Sensitivity was 100%, 94% and 75% for MGSS 13, CT scan and palpation, respectively. Specificity was 83%, 38% and 25–50% for palpation, CT scan and MGSS 13–17, respectively. Negative predictive result values were 100%, 90% and 83% for MGSS 13, CT Scan and palpation. The logistic regression analysis showed an independent predictor factor for palpation ( p = 0.001) and MGSS ( p = 0.01). The combination of MGSS and clinical palpation allowed a new design for evaluating neck metastasis in oral cancer. This method establishes 3 different groups at risk: 3 of very low (<2%), 2 of low risk (18–27%) and 1 of high risk (85%). Conclusions MGSS predicts metastasis better than CT scan and palpation. Combination of MGSS and palpation improves the prediction of metastasis.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Carcinoma, Squamous Cell - pathology</subject><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Clinical palpation</subject><subject>Computerized tomography</subject><subject>Dentistry</subject><subject>Dermatology</subject><subject>Double-Blind Method</subject><subject>Female</subject><subject>Head and neck metastasis</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Logistic Models</subject><subject>Lymph Nodes - diagnostic imaging</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis - diagnosis</subject><subject>Male</subject><subject>Martínez-Gimeno Scoring System</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mouth Neoplasms - pathology</subject><subject>Neck</subject><subject>Neck Dissection - utilization</subject><subject>Neoplasm Grading - methods</subject><subject>Oral cancer</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Palpation</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Risk Assessment</subject><subject>Squamous cell carcinoma</subject><subject>Surgery</subject><subject>Tomography, X-Ray Computed</subject><subject>Tumors</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><subject>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</subject><issn>1010-5182</issn><issn>1878-4119</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9ks2KFDEQxxtR3HX1BTxILuKpx1T6Ix2RhWHRVVjxMHoOmXS1m7Y7mU26R8Z38uIr-GIm86HgQQgkVH7_qqT-lWVPgS6AQv2yX_R6DAtG94EFZfxedg4Nb_ISQNyP53iTV9Cws-xRCD2ltKaNeJidMQBgXMB59nNJLH4jI063riWd82S6RbLx2Bo9GWeJ64hGvzVaDcS6FhOqQlwYiLEk3M1qdHOI0DAQrbw21o0qyVIi51WKbs20e0WWRLtxbaw6Jf6g_PTrh8Xv-bUZ0Tqy0s4b-4WsdmHCkSjbEj0Yuy--UcNmr3ycPejUEPDJcb_IPr998-nqXX7z8fr91fIm12VJp7wu1lwIxUTbAes4Y1QBdoKyolOsANGuoeUc4y3XdaU5iqYoaQVKVGUEeXGRvTjk3Xh3N2OY5GhC-qayGH8sm0YAbzirI8kOpPYuBI-d3HgzKr-TQGWySvYyWSWTVSkWrYqiZ8f083rE9o_k5E0Enh8BFWIDOq-sNuEvV1Y1EzxVf33gMDZja9DLoA1aHS30qCfZOvP_d1z-Iz-1_CvuMPRu9ja2WYIMTFK5SkOVZgriODHgovgNWFPKHw</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Martínez-Gimeno, Carlos</creator><creator>Rodríguez-Delgado, Luisa Elena</creator><creator>Perera-Molinero, Antonio</creator><creator>Trujillo, María del Carmen</creator><creator>Chivite, Ana</creator><creator>Maeso, Maria Carmen</creator><creator>Aguirre-Jaime, Armando</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20111001</creationdate><title>A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: A combination of Martínez-Gimeno Scoring System and clinical palpation</title><author>Martínez-Gimeno, Carlos ; Rodríguez-Delgado, Luisa Elena ; Perera-Molinero, Antonio ; Trujillo, María del Carmen ; Chivite, Ana ; Maeso, Maria Carmen ; Aguirre-Jaime, Armando</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-63b799a29df12f7220a1ef9023fa2319db1d77edf17c65c7e9834051a9541ef73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Carcinoma, Squamous Cell - pathology</topic><topic>Carcinoma, Squamous Cell - secondary</topic><topic>Clinical palpation</topic><topic>Computerized tomography</topic><topic>Dentistry</topic><topic>Dermatology</topic><topic>Double-Blind Method</topic><topic>Female</topic><topic>Head and neck metastasis</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Logistic Models</topic><topic>Lymph Nodes - diagnostic imaging</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis - diagnosis</topic><topic>Male</topic><topic>Martínez-Gimeno Scoring System</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mouth Neoplasms - pathology</topic><topic>Neck</topic><topic>Neck Dissection - utilization</topic><topic>Neoplasm Grading - methods</topic><topic>Oral cancer</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Palpation</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Risk Assessment</topic><topic>Squamous cell carcinoma</topic><topic>Surgery</topic><topic>Tomography, X-Ray Computed</topic><topic>Tumors</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><topic>Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Martínez-Gimeno, Carlos</creatorcontrib><creatorcontrib>Rodríguez-Delgado, Luisa Elena</creatorcontrib><creatorcontrib>Perera-Molinero, Antonio</creatorcontrib><creatorcontrib>Trujillo, María del Carmen</creatorcontrib><creatorcontrib>Chivite, Ana</creatorcontrib><creatorcontrib>Maeso, Maria Carmen</creatorcontrib><creatorcontrib>Aguirre-Jaime, Armando</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cranio-maxillo-facial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Martínez-Gimeno, Carlos</au><au>Rodríguez-Delgado, Luisa Elena</au><au>Perera-Molinero, Antonio</au><au>Trujillo, María del Carmen</au><au>Chivite, Ana</au><au>Maeso, Maria Carmen</au><au>Aguirre-Jaime, Armando</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: A combination of Martínez-Gimeno Scoring System and clinical palpation</atitle><jtitle>Journal of cranio-maxillo-facial surgery</jtitle><addtitle>J Craniomaxillofac Surg</addtitle><date>2011-10-01</date><risdate>2011</risdate><volume>39</volume><issue>7</issue><spage>534</spage><epage>537</epage><pages>534-537</pages><issn>1010-5182</issn><eissn>1878-4119</eissn><coden>JCMSET</coden><abstract>Abstract Aims Evaluation of the accuracy of palpation, CT scan and Martínez-Gimeno Score System in the assessment of neck nodes metastasis in squamous cell carcinoma of the oral cavity. Design This is a prospective triple blind study performed in 40 consecutive patients with squamous cell carcinoma of the oral cavity. Patients: 40 consecutive patients suffering primary oral squamous cell carcinoma, without any treatment before surgery, palpation or CT Scan. Results 40% of the cases showed metastasis in pathological study. Sensitivity was 100%, 94% and 75% for MGSS 13, CT scan and palpation, respectively. Specificity was 83%, 38% and 25–50% for palpation, CT scan and MGSS 13–17, respectively. Negative predictive result values were 100%, 90% and 83% for MGSS 13, CT Scan and palpation. The logistic regression analysis showed an independent predictor factor for palpation ( p = 0.001) and MGSS ( p = 0.01). The combination of MGSS and clinical palpation allowed a new design for evaluating neck metastasis in oral cancer. This method establishes 3 different groups at risk: 3 of very low (<2%), 2 of low risk (18–27%) and 1 of high risk (85%). Conclusions MGSS predicts metastasis better than CT scan and palpation. Combination of MGSS and palpation improves the prediction of metastasis.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>21112791</pmid><doi>10.1016/j.jcms.2010.10.027</doi><tpages>4</tpages></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - secondary Clinical palpation Computerized tomography Dentistry Dermatology Double-Blind Method Female Head and neck metastasis Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Logistic Models Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymphatic Metastasis - diagnosis Male Martínez-Gimeno Scoring System Medical sciences Middle Aged Mouth Neoplasms - pathology Neck Neck Dissection - utilization Neoplasm Grading - methods Oral cancer Otorhinolaryngology. Stomatology Palpation Predictive Value of Tests Prognosis Prospective Studies Risk Assessment Squamous cell carcinoma Surgery Tomography, X-Ray Computed Tumors Tumors of the skin and soft tissue. Premalignant lesions Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology |
| title | A new method for the prediction of cervical node metastases in squamous cell carcinoma of the oral cavity: A combination of Martínez-Gimeno Scoring System and clinical palpation |
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