Paraffin-embedded tissue blot as a sensitive method for discrimination between classical scrapie and experimental bovine spongiform encephalopathy in sheep

The paraffin-embedded tissue (PET) blot was modified for use as a tool to differentiate between classical scrapie and experimental bovine spongiform encephalopathy (BSE) in sheep. Medulla (obex) from 21 cases of classical scrapie and 6 cases of experimental ovine BSE were used to develop the method...

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Veröffentlicht in:	Journal of veterinary diagnostic investigation 2011-05, Vol.23 (3), p.492-498
Hauptverfasser:	Webb, Paul R, Denyer, Margaret, Gough, Julie, Spiropoulos, John, Simmons, Marion M, Spencer, Yvonne I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bovine spongiform encephalopathy Brain - pathology Cattle Encephalopathy, Bovine Spongiform - diagnosis Encephalopathy, Bovine Spongiform - pathology Immunoblotting - veterinary immunohistochemistry Paraffin Embedding - veterinary scrapie Scrapie - diagnosis Sensitivity and Specificity Sheep Sheep Diseases - diagnosis Sheep Diseases - pathology
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