Large-Scale Analysis Reveals Acquisition of Lineage-Specific Chromosomal Aberrations in Human Adult Stem Cells

In this study, we assessed the genetic integrity of over 400 samples of human multipotent stem cells using gene expression data sets. Our analysis reveals that neural and mesenchymal stem cells acquire characteristic large chromosomal aberrations at a similar, or somewhat lower, frequency to that se...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell stem cell 2011-08, Vol.9 (2), p.97-102
Hauptverfasser:	Ben-David, Uri, Mayshar, Yoav, Benvenisty, Nissim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Stem Cells - metabolism Adult Stem Cells - pathology Biological and medical sciences Cell differentiation, maturation, development, hematopoiesis Cell Line Cell Lineage Cell physiology Chromosome Aberrations Fundamental and applied biological sciences. Psychology Gene Expression Regulation Humans Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - pathology Molecular and cellular biology Neural Stem Cells - metabolism Neural Stem Cells - pathology Pluripotent Stem Cells - metabolism Pluripotent Stem Cells - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!