Effects of the proapoptotic regulator Bcl2/adenovirus EIB 19 kDa-interacting protein 3 on radiosensitivity of cervical cancer

Bcl2/adenovirus EIB 19 kDa-interacting protein 3 (BNIP3) is a proapoptotic member of the Bcl-2 family. To address its potential as a therapeutic target for radiosensitization, this study investigated the effect of Bnip3 expression on radiosensitivity of cervical cancer in vitro and in vivo. In vitro...

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Veröffentlicht in:	Cancer biotherapy & radiopharmaceuticals 2011-06, Vol.26 (3), p.279-286
Hauptverfasser:	Wang, Zi, Huang, Chun-mei, Deng, Qian, Zeng, Hui, Wang, Xin, Zhang, Shuang, Bi, Feng, Tang, Qiu-lin, Zhong, Ren-ming, Li, Ai-jun, He, Yin-Bo, Chen, Ni, Li, Zhi-ping, Wang, Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenovirus Adenovirus E1B Proteins - metabolism Adenoviruses Analysis Animals Care and treatment Cell Survival Cervical cancer Development and progression Female Gene expression Gene Expression Regulation, Neoplastic Genetic aspects Health aspects HeLa Cells Humans Membrane Proteins - genetics Mice Mice, Inbred BALB C Neoplasm Transplantation Plasmids - metabolism Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-bcl-2 - biosynthesis Radiation Tolerance - genetics Recombinant Proteins - metabolism Transfection Uterine Cervical Neoplasms - genetics Uterine Cervical Neoplasms - metabolism
Online-Zugang:	Volltext
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