Eszopiclone facilitation of the antidepressant efficacy of fluoxetine using a social defeat stress model

This study analyzed the interaction of the sleep aid eszopiclone (ESZ) and antidepressant fluoxetine (FLX) on social defeat stress (SDS) in the mouse. Beta adrenoreceptors, brain-derived neurotrophic factor (BDNF) and cAMP response element binding protein (CREB) expression in the hippocampus and fro...

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Veröffentlicht in:	Pharmacology, biochemistry and behavior biochemistry and behavior, 2011-10, Vol.99 (4), p.648-658
Hauptverfasser:	Brown, Russell W., Noel, Daniel M., Smith, Jessica J., Smith, Meredith L., Huggins, Kimberly N., Szebeni, Katalin, Szebeni, Attila, Duffourc, Michelle, Chandley, Michelle, Ordway, Gregory A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidepressive Agents, Second-Generation - pharmacology Azabicyclo Compounds - pharmacology Beta receptors Biological and medical sciences Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - metabolism Cyclic AMP response element binding protein Cyclic AMP Response Element-Binding Protein - metabolism Depression - drug therapy Depression - etiology Depression - psychology Dose-Response Relationship, Drug Drug Synergism Eszopiclone Fluoxetine Fluoxetine - pharmacology Hypnotics and Sedatives - pharmacology Interpersonal Relations Male Medical sciences Mice Mice, Inbred C57BL Neuropharmacology Pharmacology. Drug treatments Piperazines - pharmacology Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Real-Time Polymerase Chain Reaction Receptors, Adrenergic, beta - drug effects Receptors, Adrenergic, beta - metabolism Social defeat stress Social Environment Stress, Psychological - complications Stress, Psychological - psychology
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