Daidzein supplementation prevents non-alcoholic fatty liver disease through alternation of hepatic gene expression profiles and adipocyte metabolism

Introduction: Globally, non-alcoholic fatty liver disease (NAFLD) continues to rise and isoflavones exert antisteatotic effects by the regulation of hepatic lipogenesis/insulin resistance or adiposity/a variety of adipocytokines are related to hepatic steatosis. However, there is very little informa...

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Veröffentlicht in:	International Journal of Obesity 2011-08, Vol.35 (8), p.1019-1030
Hauptverfasser:	Kim, M.H, Park, J.S, Jung, J.W, Byun, K.W, Kang, K.S, Lee, Y.S
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443/319 631/80/86/2367 692/699/1503/1607/2750 692/700/459/1994 adipocytes Adipocytes - drug effects Adipocytes - metabolism Adipokines - metabolism adiponectin Adipose Tissue - drug effects Adipose Tissue - metabolism adiposity Animals beta oxidation binding proteins Biological and medical sciences Blood blood glucose Body Weight daidzein Diet Energy enzymes Epidemiology Fatty acids Fatty liver Fatty Liver - drug therapy Fatty Liver - metabolism Fatty Liver - prevention & control Gastroenterology. Liver. Pancreas. Abdomen Gene expression Gene Expression Profiling gene expression regulation genes Genetic aspects ghrelin Health aspects Health Promotion and Disease Prevention homeostasis insulin Insulin - metabolism Insulin Resistance Internal Medicine Isoflavones Isoflavones - pharmacology leptin lipogenesis Lipogenesis - drug effects Liver Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Medicine Medicine & Public Health messenger RNA Metabolic Diseases Metabolism Mice Mice, Inbred C57BL microarray technology Non-alcoholic Fatty Liver Disease Nutrition Obesity original-article Other diseases. Semiology Oxidation Phytoestrogens - pharmacology Prevention and actions Public Health Public health. Hygiene Public health. Hygiene-occupational medicine Reverse Transcriptase Polymerase Chain Reaction tumor necrosis factor-alpha Tumor necrosis factor-TNF Veterinary colleges
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