Defining process design space for monoclonal antibody cell culture

The concept of design space has been taking root as a foundation of in-process control strategies for biopharmaceutical manufacturing processes. During mapping of the process design space, the multidimensional combination of operational variables is studied to quantify the impact on process performa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biotechnology and bioengineering 2010-08, Vol.106 (6), p.894-905
Hauptverfasser:	Abu-Absi, Susan Fugett, Yang, LiYing, Thompson, Patrick, Jiang, Canping, Kandula, Sunitha, Schilling, Bernhard, Shukla, Abhinav A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - biosynthesis Biological and medical sciences Bioreactors Biotechnology Biotechnology - methods Cell culture Cell Culture Techniques - methods CHO Cells Cricetinae Cricetulus design space Drug Industry - methods Fundamental and applied biological sciences. Psychology Glycosylation Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Monoclonal antibodies monoclonal antibody Pharmaceuticals Production of active biomolecules quality by design Recombinant Proteins - biosynthesis Studies
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!