Interleukin-6 Regulates the Expression of Hypothalamic Neuropeptides Involved in Body Weight in a Gender-Dependent Way

Interleukin (IL)‐6 has been involved in the control of body weight and body fat. Nevertheless, the mechanisms underlying these effects are not completely understood because central and peripheral actions of IL‐6 are plausible. To gain further insight into the central effects of IL‐6, we used transge...

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Veröffentlicht in:	Journal of neuroendocrinology 2011-08, Vol.23 (8), p.675-686
Hauptverfasser:	Señarís, R. M., Trujillo, M. L., Navia, B., Comes, G., Ferrer, B., Giralt, M., Hidalgo, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Agouti-Related Protein - genetics Agouti-Related Protein - metabolism Animals Biological and medical sciences Blood Glucose - metabolism Body fat Body weight Body Weight - physiology Corticotropin-releasing hormone Corticotropin-Releasing Hormone - genetics Corticotropin-Releasing Hormone - metabolism Diet, High-Fat Energy balance Energy Metabolism Fasting Feeding Female Food Deprivation - physiology Fundamental and applied biological sciences. Psychology gender Glial fibrillary acidic protein Glucose High fat diet Homeostasis - physiology Hypothalamic Hormones - genetics Hypothalamic Hormones - metabolism Hypothalamus Hypothalamus - metabolism Interleukin 6 Interleukin-6 - genetics Interleukin-6 - metabolism Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Male Melanin-concentrating hormone Melanins - genetics Melanins - metabolism Mice Mice, Inbred C57BL Mice, Transgenic mRNA Neuropeptide Y Neuropeptide Y - genetics Neuropeptide Y - metabolism neuropeptides Neuropeptides - genetics Neuropeptides - metabolism Orexins Overexpression Pituitary Hormones - genetics Pituitary Hormones - metabolism Pro-Opiomelanocortin - genetics Pro-Opiomelanocortin - metabolism Promoters Proopiomelanocortin Sex Characteristics Transgenic mice Vertebrates: endocrinology
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