Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis
Determining the relative and absolute reliability of outcomes of physical performance tests for people undergoing hemodialysis is necessary to discriminate between the true effects of exercise interventions and the inherent variability of this cohort. The aims of this study were to assess the relati...
Gespeichert in:
Veröffentlicht in: | Physical therapy 2011-08, Vol.91 (8), p.1244-1252 |
---|---|
Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1252 |
---|---|
container_issue | 8 |
container_start_page | 1244 |
container_title | Physical therapy |
container_volume | 91 |
creator | Eva Segura-Ortí Francisco José Martínez-Olmos |
description | Determining the relative and absolute reliability of outcomes of physical performance tests for people undergoing hemodialysis is necessary to discriminate between the true effects of exercise interventions and the inherent variability of this cohort.
The aims of this study were to assess the relative reliability of sit-to-stand-to-sit tests (the STS-10, which measures the time [in seconds] required to complete 10 full stands from a sitting position, and the STS-60, which measures the number of repetitions achieved in 60 seconds), the Six-Minute Walk Test (6MWT), the one-leg heel-rise test, and the handgrip strength test and to calculate minimal detectable change (MDC) scores in people undergoing hemodialysis.
This study was a prospective, nonexperimental investigation.
Thirty-nine people undergoing hemodialysis at 2 clinics in Spain were contacted. Study participants performed the STS-10 (n=37), the STS-60 (n=37), and the 6MWT (n=36). At one of the settings, the participants also performed the one-leg heel-rise test (n=21) and the handgrip strength test (n=12) on both the right and the left sides. Participants attended 2 testing sessions 1 to 2 weeks apart.
High intraclass correlation coefficients (≥.88) were found for all tests, suggesting good relative reliability. The MDC scores at 90% confidence intervals were as follows: 8.4 seconds for the STS-10, 4 repetitions for the STS-60, 66.3 m for the 6MWT, 3.4 kg for handgrip strength (force-generating capacity), 3.7 repetitions for the one-leg heel-rise test with the right leg, and 5.2 repetitions for the one-leg heel-rise test with the left leg. Limitations A limited sample of patients was used in this study.
The STS-16, STS-60, 6MWT, one-leg heel rise test, and handgrip strength test are reliable outcome measures. The MDC scores at 90% confidence intervals for these tests will help to determine whether a change is due to error or to an intervention. |
doi_str_mv | 10.2522/ptj.20100141 |
format | Article |
fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_888106325</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A264364701</galeid><sourcerecordid>A264364701</sourcerecordid><originalsourceid>FETCH-LOGICAL-c735t-957cfd8b8171479c63942878bb4c8b3af02ebd886d1adef7bf0d60d9c8bf79ec3</originalsourceid><addsrcrecordid>eNqVk19v0zAUxSMEYmPwxjOy2ANCWoodp4n9OBVYJxWK2k08Wk5yk7q4drFdsX5EvhXun4GKKjQUybZyfvfE9s1JkpcE97J-lr1bhnkvwwRjkpNHySnpU5YWZZY_Tk4xpiTlOKMnyTPv5zgyZc6fJicZKQkvaHma_LwBH9IJhDihCWglK6VVWCNpGvRJGbWQGr2Pch1kpQENZtJ0gKa1deBRax2aqpAGm05DrNguVEAbU3-BwiyS6i6NPqsA6KvU37bSThkbSEfQoSGATifKw17bfHkYh86pJZoGB6YLM6QM-gJ2GbdwaxpwnVVmU7qwjZJ67ZV_njxppfbwYj-fJbcfP9wMhulofHU9uByldUn7IeX9sm4bVrF4BXnJ64LyPGMlq6q8ZhWVLc6gahgrGiIbaMuqxU2BGx7FtuRQ07Pkzc536ez3VdyxWChfg9bSgF15wRgjuKBZ_wEk5pxxSiP5-i9yblfOxGNEiBQlYVvofAd1UoNQprXByXpjKS6zIqdFXmISqfQI1YEBJ7U10Kr4-oDvHeHj08BC1UcL3h4URCbAXejkyntxPZ38B_v5wSy7Gv3rkHu2tlpDByL2ezA-5C92fO2s9w5asXTxz3ZrQbDYpEjEFIn7FEX81b4dq2oBzW_4PjZ__Gaqm_1QDoSPOdER3zrteseJYIJkeU5_AX47Ivw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>881671833</pqid></control><display><type>article</type><title>Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Eva Segura-Ortí ; Francisco José Martínez-Olmos</creator><creatorcontrib>Eva Segura-Ortí ; Francisco José Martínez-Olmos</creatorcontrib><description>Determining the relative and absolute reliability of outcomes of physical performance tests for people undergoing hemodialysis is necessary to discriminate between the true effects of exercise interventions and the inherent variability of this cohort.
The aims of this study were to assess the relative reliability of sit-to-stand-to-sit tests (the STS-10, which measures the time [in seconds] required to complete 10 full stands from a sitting position, and the STS-60, which measures the number of repetitions achieved in 60 seconds), the Six-Minute Walk Test (6MWT), the one-leg heel-rise test, and the handgrip strength test and to calculate minimal detectable change (MDC) scores in people undergoing hemodialysis.
This study was a prospective, nonexperimental investigation.
Thirty-nine people undergoing hemodialysis at 2 clinics in Spain were contacted. Study participants performed the STS-10 (n=37), the STS-60 (n=37), and the 6MWT (n=36). At one of the settings, the participants also performed the one-leg heel-rise test (n=21) and the handgrip strength test (n=12) on both the right and the left sides. Participants attended 2 testing sessions 1 to 2 weeks apart.
High intraclass correlation coefficients (≥.88) were found for all tests, suggesting good relative reliability. The MDC scores at 90% confidence intervals were as follows: 8.4 seconds for the STS-10, 4 repetitions for the STS-60, 66.3 m for the 6MWT, 3.4 kg for handgrip strength (force-generating capacity), 3.7 repetitions for the one-leg heel-rise test with the right leg, and 5.2 repetitions for the one-leg heel-rise test with the left leg. Limitations A limited sample of patients was used in this study.
The STS-16, STS-60, 6MWT, one-leg heel rise test, and handgrip strength test are reliable outcome measures. The MDC scores at 90% confidence intervals for these tests will help to determine whether a change is due to error or to an intervention.</description><identifier>ISSN: 0031-9023</identifier><identifier>EISSN: 1538-6724</identifier><identifier>DOI: 10.2522/ptj.20100141</identifier><identifier>PMID: 21719637</identifier><language>eng</language><publisher>United States: American Physical Therapy Association</publisher><subject>Clinical medicine ; Comorbidity ; Disability Evaluation ; Exercise therapy ; Family medical history ; Female ; Hand Strength - physiology ; Hemodialysis ; Humans ; Male ; Methods ; Middle Aged ; Motor ability ; Older people ; Patient outcomes ; Physical therapy ; Prospective Studies ; Renal Dialysis ; Reproducibility of Results ; Statistics, Nonparametric ; Walking - physiology</subject><ispartof>Physical therapy, 2011-08, Vol.91 (8), p.1244-1252</ispartof><rights>COPYRIGHT 2011 Oxford University Press</rights><rights>COPYRIGHT 2011 Oxford University Press</rights><rights>Copyright AMERICAN PHYSICAL THERAPY ASSOCIATION Aug 2011</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c735t-957cfd8b8171479c63942878bb4c8b3af02ebd886d1adef7bf0d60d9c8bf79ec3</citedby><cites>FETCH-LOGICAL-c735t-957cfd8b8171479c63942878bb4c8b3af02ebd886d1adef7bf0d60d9c8bf79ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21719637$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eva Segura-Ortí</creatorcontrib><creatorcontrib>Francisco José Martínez-Olmos</creatorcontrib><title>Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis</title><title>Physical therapy</title><addtitle>Phys Ther</addtitle><description>Determining the relative and absolute reliability of outcomes of physical performance tests for people undergoing hemodialysis is necessary to discriminate between the true effects of exercise interventions and the inherent variability of this cohort.
The aims of this study were to assess the relative reliability of sit-to-stand-to-sit tests (the STS-10, which measures the time [in seconds] required to complete 10 full stands from a sitting position, and the STS-60, which measures the number of repetitions achieved in 60 seconds), the Six-Minute Walk Test (6MWT), the one-leg heel-rise test, and the handgrip strength test and to calculate minimal detectable change (MDC) scores in people undergoing hemodialysis.
This study was a prospective, nonexperimental investigation.
Thirty-nine people undergoing hemodialysis at 2 clinics in Spain were contacted. Study participants performed the STS-10 (n=37), the STS-60 (n=37), and the 6MWT (n=36). At one of the settings, the participants also performed the one-leg heel-rise test (n=21) and the handgrip strength test (n=12) on both the right and the left sides. Participants attended 2 testing sessions 1 to 2 weeks apart.
High intraclass correlation coefficients (≥.88) were found for all tests, suggesting good relative reliability. The MDC scores at 90% confidence intervals were as follows: 8.4 seconds for the STS-10, 4 repetitions for the STS-60, 66.3 m for the 6MWT, 3.4 kg for handgrip strength (force-generating capacity), 3.7 repetitions for the one-leg heel-rise test with the right leg, and 5.2 repetitions for the one-leg heel-rise test with the left leg. Limitations A limited sample of patients was used in this study.
The STS-16, STS-60, 6MWT, one-leg heel rise test, and handgrip strength test are reliable outcome measures. The MDC scores at 90% confidence intervals for these tests will help to determine whether a change is due to error or to an intervention.</description><subject>Clinical medicine</subject><subject>Comorbidity</subject><subject>Disability Evaluation</subject><subject>Exercise therapy</subject><subject>Family medical history</subject><subject>Female</subject><subject>Hand Strength - physiology</subject><subject>Hemodialysis</subject><subject>Humans</subject><subject>Male</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Motor ability</subject><subject>Older people</subject><subject>Patient outcomes</subject><subject>Physical therapy</subject><subject>Prospective Studies</subject><subject>Renal Dialysis</subject><subject>Reproducibility of Results</subject><subject>Statistics, Nonparametric</subject><subject>Walking - physiology</subject><issn>0031-9023</issn><issn>1538-6724</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqVk19v0zAUxSMEYmPwxjOy2ANCWoodp4n9OBVYJxWK2k08Wk5yk7q4drFdsX5EvhXun4GKKjQUybZyfvfE9s1JkpcE97J-lr1bhnkvwwRjkpNHySnpU5YWZZY_Tk4xpiTlOKMnyTPv5zgyZc6fJicZKQkvaHma_LwBH9IJhDihCWglK6VVWCNpGvRJGbWQGr2Pch1kpQENZtJ0gKa1deBRax2aqpAGm05DrNguVEAbU3-BwiyS6i6NPqsA6KvU37bSThkbSEfQoSGATifKw17bfHkYh86pJZoGB6YLM6QM-gJ2GbdwaxpwnVVmU7qwjZJ67ZV_njxppfbwYj-fJbcfP9wMhulofHU9uByldUn7IeX9sm4bVrF4BXnJ64LyPGMlq6q8ZhWVLc6gahgrGiIbaMuqxU2BGx7FtuRQ07Pkzc536ez3VdyxWChfg9bSgF15wRgjuKBZ_wEk5pxxSiP5-i9yblfOxGNEiBQlYVvofAd1UoNQprXByXpjKS6zIqdFXmISqfQI1YEBJ7U10Kr4-oDvHeHj08BC1UcL3h4URCbAXejkyntxPZ38B_v5wSy7Gv3rkHu2tlpDByL2ezA-5C92fO2s9w5asXTxz3ZrQbDYpEjEFIn7FEX81b4dq2oBzW_4PjZ__Gaqm_1QDoSPOdER3zrteseJYIJkeU5_AX47Ivw</recordid><startdate>20110801</startdate><enddate>20110801</enddate><creator>Eva Segura-Ortí</creator><creator>Francisco José Martínez-Olmos</creator><general>American Physical Therapy Association</general><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8GL</scope><scope>ISN</scope><scope>ISR</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>U9A</scope><scope>7X8</scope></search><sort><creationdate>20110801</creationdate><title>Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis</title><author>Eva Segura-Ortí ; Francisco José Martínez-Olmos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c735t-957cfd8b8171479c63942878bb4c8b3af02ebd886d1adef7bf0d60d9c8bf79ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Clinical medicine</topic><topic>Comorbidity</topic><topic>Disability Evaluation</topic><topic>Exercise therapy</topic><topic>Family medical history</topic><topic>Female</topic><topic>Hand Strength - physiology</topic><topic>Hemodialysis</topic><topic>Humans</topic><topic>Male</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Motor ability</topic><topic>Older people</topic><topic>Patient outcomes</topic><topic>Physical therapy</topic><topic>Prospective Studies</topic><topic>Renal Dialysis</topic><topic>Reproducibility of Results</topic><topic>Statistics, Nonparametric</topic><topic>Walking - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eva Segura-Ortí</creatorcontrib><creatorcontrib>Francisco José Martínez-Olmos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Gale In Context: High School</collection><collection>Gale In Context: Canada</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Career & Technical Education Database</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Physical therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eva Segura-Ortí</au><au>Francisco José Martínez-Olmos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis</atitle><jtitle>Physical therapy</jtitle><addtitle>Phys Ther</addtitle><date>2011-08-01</date><risdate>2011</risdate><volume>91</volume><issue>8</issue><spage>1244</spage><epage>1252</epage><pages>1244-1252</pages><issn>0031-9023</issn><eissn>1538-6724</eissn><abstract>Determining the relative and absolute reliability of outcomes of physical performance tests for people undergoing hemodialysis is necessary to discriminate between the true effects of exercise interventions and the inherent variability of this cohort.
The aims of this study were to assess the relative reliability of sit-to-stand-to-sit tests (the STS-10, which measures the time [in seconds] required to complete 10 full stands from a sitting position, and the STS-60, which measures the number of repetitions achieved in 60 seconds), the Six-Minute Walk Test (6MWT), the one-leg heel-rise test, and the handgrip strength test and to calculate minimal detectable change (MDC) scores in people undergoing hemodialysis.
This study was a prospective, nonexperimental investigation.
Thirty-nine people undergoing hemodialysis at 2 clinics in Spain were contacted. Study participants performed the STS-10 (n=37), the STS-60 (n=37), and the 6MWT (n=36). At one of the settings, the participants also performed the one-leg heel-rise test (n=21) and the handgrip strength test (n=12) on both the right and the left sides. Participants attended 2 testing sessions 1 to 2 weeks apart.
High intraclass correlation coefficients (≥.88) were found for all tests, suggesting good relative reliability. The MDC scores at 90% confidence intervals were as follows: 8.4 seconds for the STS-10, 4 repetitions for the STS-60, 66.3 m for the 6MWT, 3.4 kg for handgrip strength (force-generating capacity), 3.7 repetitions for the one-leg heel-rise test with the right leg, and 5.2 repetitions for the one-leg heel-rise test with the left leg. Limitations A limited sample of patients was used in this study.
The STS-16, STS-60, 6MWT, one-leg heel rise test, and handgrip strength test are reliable outcome measures. The MDC scores at 90% confidence intervals for these tests will help to determine whether a change is due to error or to an intervention.</abstract><cop>United States</cop><pub>American Physical Therapy Association</pub><pmid>21719637</pmid><doi>10.2522/ptj.20100141</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0031-9023 |
ispartof | Physical therapy, 2011-08, Vol.91 (8), p.1244-1252 |
issn | 0031-9023 1538-6724 |
language | eng |
recordid | cdi_proquest_miscellaneous_888106325 |
source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
subjects | Clinical medicine Comorbidity Disability Evaluation Exercise therapy Family medical history Female Hand Strength - physiology Hemodialysis Humans Male Methods Middle Aged Motor ability Older people Patient outcomes Physical therapy Prospective Studies Renal Dialysis Reproducibility of Results Statistics, Nonparametric Walking - physiology |
title | Test-Retest Reliability and Minimal Detectable Change Scores for Sit-to-Stand-to-Sit Tests, the Six-Minute Walk Test, the One-Leg Heel-Rise Test, and Handgrip Strength in People Undergoing Hemodialysis |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T02%3A33%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Test-Retest%20Reliability%20and%20Minimal%20Detectable%20Change%20Scores%20for%20Sit-to-Stand-to-Sit%20Tests,%20the%20Six-Minute%20Walk%20Test,%20the%20One-Leg%20Heel-Rise%20Test,%20and%20Handgrip%20Strength%20in%20People%20Undergoing%20Hemodialysis&rft.jtitle=Physical%20therapy&rft.au=Eva%20Segura-Ort%C3%AD&rft.date=2011-08-01&rft.volume=91&rft.issue=8&rft.spage=1244&rft.epage=1252&rft.pages=1244-1252&rft.issn=0031-9023&rft.eissn=1538-6724&rft_id=info:doi/10.2522/ptj.20100141&rft_dat=%3Cgale_proqu%3EA264364701%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=881671833&rft_id=info:pmid/21719637&rft_galeid=A264364701&rfr_iscdi=true |