Citrate synthase in Corynebacterium glutamicum is encoded by two gltA transcripts which are controlled by RamA, RamB, and GlxR

Citrate synthase (CS) is located at a major branch point in the metabolism and is required for both tricarboxylic acid and glyoxylic acid cycle activity. Here we show that the CS gene gltA of Corynebacterium glutamicum is monocistronic, but that two transcripts are formed with their transcript initi...

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Veröffentlicht in:	Journal of biotechnology 2011-07, Vol.154 (2), p.140-148
Hauptverfasser:	van Ooyen, Jan, Emer, Denise, Bussmann, Michael, Bott, Michael, Eikmanns, Bernhard J., Eggeling, Lothar
Format:	Artikel
Sprache:	eng
Schlagworte:	acetates Acetates - metabolism Bacterial Proteins - genetics Bacterial Proteins - metabolism biotechnology citrate (si)-synthase Citrate (si)-Synthase - genetics Citrate (si)-Synthase - metabolism Citrate synthase Codon, Initiator Corynebacterium glutamicum Corynebacterium glutamicum - enzymology Corynebacterium glutamicum - genetics Expression control Gene Expression Regulation, Bacterial gene overexpression glucose Glucose - metabolism GlxR glyoxylic acid Metabolic Networks and Pathways - genetics metabolism mutants Northern blotting promoter regions Promoter Regions, Genetic proteins RamA RamB reporter genes start codon Transcript formation transcription factors Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic translation (genetics)
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