Dipeptidyl peptidase IV (DPP4) deficiency increases Th1-driven allergic contact dermatitis

Summary Background CD26 or dipeptidyl peptidase IV (DPP4) is known to be involved in several immunological processes and has recently been reported to play a crucial role in the allergic responses of the lungs. Objectives To explore the impact of DPP4 on the allergic response of the skin. Methods Sk...

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Veröffentlicht in:	Clinical and experimental allergy 2011-08, Vol.41 (8), p.1098-1107
Hauptverfasser:	Tasic, T., Bäumer, W., Schmiedl, A., Schwichtenhövel, F., Pabst, R., Raap, U., von Hörsten, S., Stephan, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Animals, Congenic Asthma Atopic dermatitis Biological and medical sciences Biopsy CD26 CD26 antigen Cells, Cultured Contact dermatitis contact hypersensitivity Dermatitis, Allergic Contact - immunology Dermatitis, Atopic - immunology Diabetes mellitus Dipeptidyl Peptidase 4 - deficiency Dipeptidyl Peptidase 4 - immunology Dipeptidyl Peptidase 4 - metabolism Enzyme-linked immunosorbent assay Flow cytometry Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Regulation Helper cells Humans Hypersensitivity Inflammation Inflammatory diseases Lung Lymphocytes T Rats Skin diseases Skin Tests Th1 Cells - immunology
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