Wound botulism in drug users: a still underestimated diagnosis
Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset o...
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Veröffentlicht in: | Neurological sciences 2010-12, Vol.31 (6), p.825-827 |
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creator | Rodolico, C. Barca, E. Fenicia, L. Anniballi, F. Sinardi, A. U. Girlanda, P. |
description | Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset of slurred speech and dysphagia. The most considerable finding of electrophysiological study was the reduction in amplitude of compound muscle action potential which should be considered a useful initial electrodiagnostic sign in the clinical context of botulism. Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications. |
doi_str_mv | 10.1007/s10072-010-0350-1 |
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Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications.</description><identifier>ISSN: 1590-1874</identifier><identifier>EISSN: 1590-3478</identifier><identifier>DOI: 10.1007/s10072-010-0350-1</identifier><identifier>PMID: 20552239</identifier><language>eng</language><publisher>Milan: Springer Milan</publisher><subject>Botulism - diagnosis ; Botulism - transmission ; Case Report ; Clostridium botulinum - pathogenicity ; Diagnosis, Differential ; Fatal Outcome ; Heroin Dependence - complications ; Heroin Dependence - diagnosis ; Heroin Dependence - microbiology ; Humans ; Injections, Intramuscular - adverse effects ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neurology ; Neuroradiology ; Neurosciences ; Neurosurgery ; Psychiatry ; Skin - injuries ; Wounds and Injuries - diagnosis ; Wounds and Injuries - microbiology</subject><ispartof>Neurological sciences, 2010-12, Vol.31 (6), p.825-827</ispartof><rights>Springer-Verlag 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c402t-cde7a0a2bfd5c47316f88fb8e27dbfe6c9ca35dd29e10fe688f5f6342ba9ecf23</citedby><cites>FETCH-LOGICAL-c402t-cde7a0a2bfd5c47316f88fb8e27dbfe6c9ca35dd29e10fe688f5f6342ba9ecf23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10072-010-0350-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10072-010-0350-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20552239$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rodolico, C.</creatorcontrib><creatorcontrib>Barca, E.</creatorcontrib><creatorcontrib>Fenicia, L.</creatorcontrib><creatorcontrib>Anniballi, F.</creatorcontrib><creatorcontrib>Sinardi, A. U.</creatorcontrib><creatorcontrib>Girlanda, P.</creatorcontrib><title>Wound botulism in drug users: a still underestimated diagnosis</title><title>Neurological sciences</title><addtitle>Neurol Sci</addtitle><addtitle>Neurol Sci</addtitle><description>Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset of slurred speech and dysphagia. The most considerable finding of electrophysiological study was the reduction in amplitude of compound muscle action potential which should be considered a useful initial electrodiagnostic sign in the clinical context of botulism. Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications.</description><subject>Botulism - diagnosis</subject><subject>Botulism - transmission</subject><subject>Case Report</subject><subject>Clostridium botulinum - pathogenicity</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Heroin Dependence - complications</subject><subject>Heroin Dependence - diagnosis</subject><subject>Heroin Dependence - microbiology</subject><subject>Humans</subject><subject>Injections, Intramuscular - adverse effects</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Psychiatry</subject><subject>Skin - injuries</subject><subject>Wounds and Injuries - diagnosis</subject><subject>Wounds and Injuries - microbiology</subject><issn>1590-1874</issn><issn>1590-3478</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE1LxDAQhoMorq7-AC8SvHiqTpKmTT0IsvgFC14UjyHNx9KlH2vSHPz3ZumqIHiZmTDPvDN5ETojcEUAyuuwjTQDAhkwDhnZQ0eEV5CxvBT7u5qIMp-h4xDWAEBywg7RjALnlLLqCN2-D7E3uB7G2Dahw02PjY8rHIP14QYrHMambXFirLep7tRoDTaNWvVDaMIJOnCqDfZ0l-fo7eH-dfGULV8enxd3y0znQMdMG1sqULR2huu8ZKRwQrhaWFqa2tlCV1oxbgytLIH0Tk3uCpbTWlVWO8rm6HLS3fjhI6ZDZNcEbdtW9XaIQQohoCJVzhN58YdcD9H36TgpoORQFKRIEJkg7YcQvHVy49PX_KckILemyslamayVW2slSTPnO-FYd9b8THx7mQA6ASG1-pX1v5v_V_0CBf2D_g</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Rodolico, C.</creator><creator>Barca, E.</creator><creator>Fenicia, L.</creator><creator>Anniballi, F.</creator><creator>Sinardi, A. 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U. ; Girlanda, P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c402t-cde7a0a2bfd5c47316f88fb8e27dbfe6c9ca35dd29e10fe688f5f6342ba9ecf23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Botulism - diagnosis</topic><topic>Botulism - transmission</topic><topic>Case Report</topic><topic>Clostridium botulinum - pathogenicity</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Heroin Dependence - complications</topic><topic>Heroin Dependence - diagnosis</topic><topic>Heroin Dependence - microbiology</topic><topic>Humans</topic><topic>Injections, Intramuscular - adverse effects</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Psychiatry</topic><topic>Skin - injuries</topic><topic>Wounds and Injuries - diagnosis</topic><topic>Wounds and Injuries - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodolico, C.</creatorcontrib><creatorcontrib>Barca, E.</creatorcontrib><creatorcontrib>Fenicia, L.</creatorcontrib><creatorcontrib>Anniballi, F.</creatorcontrib><creatorcontrib>Sinardi, A. 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U.</au><au>Girlanda, P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Wound botulism in drug users: a still underestimated diagnosis</atitle><jtitle>Neurological sciences</jtitle><stitle>Neurol Sci</stitle><addtitle>Neurol Sci</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>31</volume><issue>6</issue><spage>825</spage><epage>827</epage><pages>825-827</pages><issn>1590-1874</issn><eissn>1590-3478</eissn><abstract>Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset of slurred speech and dysphagia. The most considerable finding of electrophysiological study was the reduction in amplitude of compound muscle action potential which should be considered a useful initial electrodiagnostic sign in the clinical context of botulism. Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications.</abstract><cop>Milan</cop><pub>Springer Milan</pub><pmid>20552239</pmid><doi>10.1007/s10072-010-0350-1</doi><tpages>3</tpages></addata></record> |
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subjects | Botulism - diagnosis Botulism - transmission Case Report Clostridium botulinum - pathogenicity Diagnosis, Differential Fatal Outcome Heroin Dependence - complications Heroin Dependence - diagnosis Heroin Dependence - microbiology Humans Injections, Intramuscular - adverse effects Male Medicine Medicine & Public Health Middle Aged Neurology Neuroradiology Neurosciences Neurosurgery Psychiatry Skin - injuries Wounds and Injuries - diagnosis Wounds and Injuries - microbiology |
title | Wound botulism in drug users: a still underestimated diagnosis |
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