Wound botulism in drug users: a still underestimated diagnosis

Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset o...

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Veröffentlicht in:Neurological sciences 2010-12, Vol.31 (6), p.825-827
Hauptverfasser: Rodolico, C., Barca, E., Fenicia, L., Anniballi, F., Sinardi, A. U., Girlanda, P.
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container_end_page 827
container_issue 6
container_start_page 825
container_title Neurological sciences
container_volume 31
creator Rodolico, C.
Barca, E.
Fenicia, L.
Anniballi, F.
Sinardi, A. U.
Girlanda, P.
description Wound botulism is a rare infectious disease that is becoming a frequent complication of parental drug use. Diagnosis is often difficult and based on clinical suspicion. We report the first Italian case of wound botulism due to intramuscular heroin injection in a 48-year-old man with an acute onset of slurred speech and dysphagia. The most considerable finding of electrophysiological study was the reduction in amplitude of compound muscle action potential which should be considered a useful initial electrodiagnostic sign in the clinical context of botulism. Alerting clinicians to botulism is crucial for a rapid diagnosis and appropriate treatment and thus decreasing mortality and complications.
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subjects Botulism - diagnosis
Botulism - transmission
Case Report
Clostridium botulinum - pathogenicity
Diagnosis, Differential
Fatal Outcome
Heroin Dependence - complications
Heroin Dependence - diagnosis
Heroin Dependence - microbiology
Humans
Injections, Intramuscular - adverse effects
Male
Medicine
Medicine & Public Health
Middle Aged
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Psychiatry
Skin - injuries
Wounds and Injuries - diagnosis
Wounds and Injuries - microbiology
title Wound botulism in drug users: a still underestimated diagnosis
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