The Effect of Glycosylation on the Folding Kinetics of Erythropoietin

Glycosylation is a common posttranslational modification that generally increases protein solubility and thermodynamic stability. Less is known about how this modification influences protein folding, particularly folding processes involving intermediate species. In the present report, folding compar...

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Veröffentlicht in:	Journal of molecular biology 2011-09, Vol.412 (3), p.536-550
1. Verfasser:	Banks, Douglas D.
Format:	Artikel
Sprache:	eng
Schlagworte:	aggregation equilibrium unfolding erythropoietin Erythropoietin - chemistry Erythropoietin - metabolism Glycosylation Kinetics Models, Molecular mutants post-translational modification Protein Folding protein solubility
Online-Zugang:	Volltext
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