Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses

Background: The rate of recovery of platelet function after discontinuation of P2Y12 inhibitors depends on the reversibility of the antiplatelet effect and the extent of the on‐treatment response. P2Y12 inhibition increases the bleeding risk in patients requiring surgery. Objectives: To evaluate rec...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2011-09, Vol.9 (9), p.1730-1737
Hauptverfasser:	STOREY, R. F., BLIDEN, K. P., ECOB, R., KARUNAKARAN, A., BUTLER, K., WEI, C., TANTRY, U., GURBEL, P. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - administration & dosage Adenosine - analogs & derivatives Adult Aged Aged, 80 and over antiplatelet therapy Blood Platelets - drug effects Blood Platelets - physiology clopidogrel coronary artery disease Coronary Artery Disease - blood Coronary Artery Disease - drug therapy Double-Blind Method Female Humans Male Middle Aged Platelet Aggregation Inhibitors - administration & dosage Platelet Function Tests Purinergic P2Y Receptor Antagonists - administration & dosage ticagrelor Ticlopidine - administration & dosage Ticlopidine - analogs & derivatives Time Factors
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