Crushing Artifacts Resulting in Small Blue Cellular Clusters That Simulate Small Cell Carcinoma
The presence of “crushing” artifacts in histological sections is a very common finding and represents a potentially major pitfall for the surgical pathologist, particularly in small biopsy specimens. Microscopically, it appears as bluish clusters in which the cellular details are not recognizable. H...
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Veröffentlicht in: | International journal of surgical pathology 2011-08, Vol.19 (4), p.487-491 |
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container_title | International journal of surgical pathology |
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creator | Flamminio, Federica Tosi, Anna Lisa Fellegara, Giovanni |
description | The presence of “crushing” artifacts in histological sections is a very common finding and represents a potentially major pitfall for the surgical pathologist, particularly in small biopsy specimens. Microscopically, it appears as bluish clusters in which the cellular details are not recognizable. Here the authors report examples of this phenomenon that have been reported or that they have personally observed and emphasize some diagnostic clue to avoid its overinterpretation and the dire clinical consequences that this may entail. |
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subjects | Biopsy, Needle Carcinoid Tumor - diagnosis Carcinoma, Small Cell - diagnosis Diagnosis, Differential Diagnostic Errors - prevention & control Dura Mater - pathology Hematopoiesis, Extramedullary Histocytological Preparation Techniques - methods Humans Lung Neoplasms - diagnosis Lymphoid Tissue - pathology Male Spermatocele - diagnosis Testicular Hydrocele - diagnosis Thyroid Diseases - diagnosis Urinary Bladder - pathology |
title | Crushing Artifacts Resulting in Small Blue Cellular Clusters That Simulate Small Cell Carcinoma |
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