Respiratory complex I: ‘steam engine’ of the cell?

[Display omitted] ► Structures of reduced hydrophilic domain show how NADH interacts with enzyme. ► Architectures of the membrane domain and of the entire bacterial complex I determined. ► Mitochondrial enzyme analysed, contains long helix HL similar to bacterial structure. ► Comparison of bacterial...

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Veröffentlicht in:	Current opinion in structural biology 2011-08, Vol.21 (4), p.532-540
Hauptverfasser:	Efremov, Rouslan G, Sazanov, Leonid A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Cells - cytology Cells - enzymology Electron Transport Complex I - chemistry Electron Transport Complex I - metabolism Humans Hydrophobic and Hydrophilic Interactions Mitochondria - enzymology Protein Structure, Tertiary
Online-Zugang:	Volltext
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