Effects of Donor Age, Gender, and In Vitro Cellular Aging on the Phenotypic, Functional, and Molecular Characteristics of Mouse Bone Marrow-Derived Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are a very important adult stem cell population with a multitude of potential applications in regenerative medicine. The thorough characterization of the bone marrow MSC (BM-MSC) population derived from the BALB/c species was essential, considering the significance of t...

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Veröffentlicht in:	Stem cells and development 2011-09, Vol.20 (9), p.1549-1561
Hauptverfasser:	Katsara, Olga, Mahaira, Louisa G., Iliopoulou, Eleni G., Moustaki, Ardiana, Antsaklis, Aristidis, Loutradis, Dimitrios, Stefanidis, Konstantinos, Baxevanis, Constantin N., Papamichail, Michael, Perez, Sonia A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Antigens, Differentiation - metabolism Bone Marrow Cells - cytology Cell Differentiation Cell Proliferation Cell Size Cells, Cultured Cellular Senescence Female Gene Expression Profiling Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Male Mesenchymal Stromal Cells - metabolism Mesenchymal Stromal Cells - physiology Mice Mice, Inbred BALB C Nanog Homeobox Protein Octamer Transcription Factor-3 - genetics Octamer Transcription Factor-3 - metabolism Original Research Reports Phenotype RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism SOXB1 Transcription Factors - genetics SOXB1 Transcription Factors - metabolism
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