No major genes in autoimmune thyroid diseases: complex segregation and epidemiological studies in a large Tunisian pedigree
The autoimmune thyroid diseases (AITDs) include, Graves disease (GD), autoimmune hypothyroidism (AH): Hashimotos thyroiditis (HT) and atrophic autoimmune thyroiditis (AAT). These are prevalent autoimmune diseases, affecting up to 2% of the general population. A widely accepted model for the pathogen...
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| Veröffentlicht in: | Journal of genetics 2011-08, Vol.90 (2), p.333-337 |
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| creator | BOUGACHA-ELLEUCH, NOURA ARAB, SAIDA BEN REBAI, AHMED MNIF, MOUNA MAALEJ, ABDELLATIF CHARFI, NADIA LASSOUAD, MOHAMED BEN JOUIDA, JOMAA ABID, MOHAMED AYADI, HAMMADI |
| description | The autoimmune thyroid diseases (AITDs) include, Graves disease (GD), autoimmune hypothyroidism (AH): Hashimotos thyroiditis (HT) and atrophic autoimmune thyroiditis (AAT). These are prevalent autoimmune diseases, affecting up to 2% of the general population. A widely accepted model for the pathogenesis of AITDs suggests that each subject has a inherited background predisposition to autoimmunity, with additional environmental and hormonal factors that trigger or contribute to the development of disease. |
| doi_str_mv | 10.1007/s12041-011-0064-z |
| format | Article |
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| subjects | Adult Aged Aged, 80 and over Animal Genetics and Genomics Autoimmune diseases Biomedical and Life Sciences Case-Control Studies Consanguinity Data Interpretation, Statistical Epidemiology Evolutionary Biology Female Gene Frequency Graves Disease - epidemiology Graves Disease - genetics Heredity Humans Incidence Life Sciences Male Microbial Genetics and Genomics Middle Aged Pedigree Plant Genetics and Genomics Prevalence Research Note Thyroid diseases Thyroiditis, Autoimmune - epidemiology Thyroiditis, Autoimmune - genetics Tunisia - epidemiology Young Adult |
| title | No major genes in autoimmune thyroid diseases: complex segregation and epidemiological studies in a large Tunisian pedigree |
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