Hyperbaric Oxygenation Therapy Alleviates Chronic Constrictive Injury–Induced Neuropathic Pain and Reduces Tumor Necrosis Factor-Alpha Production

The development of hyperalgesia and allodynia after chronic constrictive injury (CCI) is associated with significantly increased tumor necrosis factor (TNF)-α and interleukin (IL)-1β. Theoretically, if the production of TNF-α and/or IL-1β could be reduced, neuropathic pain syndrome may be alleviated...

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Veröffentlicht in:	Anesthesia and analgesia 2011-09, Vol.113 (3), p.626-633
Hauptverfasser:	Li, Fenghua, Fang, Lili, Huang, Shiwei, Yang, Zhongjin, Nandi, Jyotirmoy, Thomas, Sebastian, Chen, Chung, Camporesi, Enrico
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of Variance Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Behavior, Animal Biological and medical sciences Blotting, Western Chronic Disease Disease Models, Animal Down-Regulation Hyperalgesia - immunology Hyperalgesia - physiopathology Hyperalgesia - psychology Hyperalgesia - therapy Hyperbaric Oxygenation Inflammation Mediators - metabolism Interleukin-1beta - metabolism Ligation Male Medical sciences Neuralgia - immunology Neuralgia - physiopathology Neuralgia - psychology Neuralgia - therapy Pain Measurement Pain Threshold Rats Rats, Sprague-Dawley Sciatic Nerve - immunology Sciatic Nerve - physiopathology Sciatic Nerve - surgery Time Factors Tumor Necrosis Factor-alpha - metabolism
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