An unusual cause of upper gastrointestinal bleeding: duodenal GIST. A case report and literature review
A duodenal GIST is an unusual cause of upper gastrointestinal bleeding. Duodenal GISTs are rare and constitute 5% of all GISTs. A significant percentage of duodenal GISTs are located in the third and fourth portion of the duodenum and may not be detected on routine upper endoscopy. Push enteroscopy...
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| Veröffentlicht in: | Acta gastro-enterologica belgica 2011-06, Vol.74 (2), p.347-351 |
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| creator | MEHTA, Chinar GUMASTE, Vivek V LEYTIN, Anatoly WALFISH, Aaron |
| description | A duodenal GIST is an unusual cause of upper gastrointestinal bleeding. Duodenal GISTs are rare and constitute 5% of all GISTs. A significant percentage of duodenal GISTs are located in the third and fourth portion of the duodenum and may not be detected on routine upper endoscopy. Push enteroscopy is necessary to locate these lesions. It is extremely important to differentiate a duodenal GIST from other submucosal tumors like leiomyomas, leiomyosarcomas or leiomyoblastomas which may present in a similar manner, because the treatment and prognosis differ significantly. Appropriate histological and immunohistiochemical staining is required to confirm the diagnosis. Surgical resection is the treatment of choice and may involve limited resection or a pancreaticoduodenectomy. Adjuvant therapy with Imatinib has been shown to prolong survival in patients with GIST in general. |
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Surgical resection is the treatment of choice and may involve limited resection or a pancreaticoduodenectomy. Adjuvant therapy with Imatinib has been shown to prolong survival in patients with GIST in general.</description><identifier>ISSN: 1784-3227</identifier><identifier>PMID: 21861323</identifier><language>eng</language><publisher>Brussels: Société Royale Belge de Gastro-Entérologie</publisher><subject>Adult ; Biological and medical sciences ; Diagnosis, Differential ; Duodenal Neoplasms - complications ; Duodenal Neoplasms - diagnosis ; Endoscopy, Gastrointestinal ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Gastrointestinal Hemorrhage - diagnosis ; Gastrointestinal Hemorrhage - etiology ; Gastrointestinal Stromal Tumors - complications ; Gastrointestinal Stromal Tumors - diagnosis ; Humans ; Medical sciences ; Other diseases. Semiology ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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A case report and literature review</title><title>Acta gastro-enterologica belgica</title><addtitle>Acta Gastroenterol Belg</addtitle><description>A duodenal GIST is an unusual cause of upper gastrointestinal bleeding. Duodenal GISTs are rare and constitute 5% of all GISTs. A significant percentage of duodenal GISTs are located in the third and fourth portion of the duodenum and may not be detected on routine upper endoscopy. Push enteroscopy is necessary to locate these lesions. It is extremely important to differentiate a duodenal GIST from other submucosal tumors like leiomyomas, leiomyosarcomas or leiomyoblastomas which may present in a similar manner, because the treatment and prognosis differ significantly. Appropriate histological and immunohistiochemical staining is required to confirm the diagnosis. Surgical resection is the treatment of choice and may involve limited resection or a pancreaticoduodenectomy. Adjuvant therapy with Imatinib has been shown to prolong survival in patients with GIST in general.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Diagnosis, Differential</subject><subject>Duodenal Neoplasms - complications</subject><subject>Duodenal Neoplasms - diagnosis</subject><subject>Endoscopy, Gastrointestinal</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Gastrointestinal Hemorrhage - diagnosis</subject><subject>Gastrointestinal Hemorrhage - etiology</subject><subject>Gastrointestinal Stromal Tumors - complications</subject><subject>Gastrointestinal Stromal Tumors - diagnosis</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. 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Abdomen</topic><topic>Gastrointestinal Hemorrhage - diagnosis</topic><topic>Gastrointestinal Hemorrhage - etiology</topic><topic>Gastrointestinal Stromal Tumors - complications</topic><topic>Gastrointestinal Stromal Tumors - diagnosis</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MEHTA, Chinar</creatorcontrib><creatorcontrib>GUMASTE, Vivek V</creatorcontrib><creatorcontrib>LEYTIN, Anatoly</creatorcontrib><creatorcontrib>WALFISH, Aaron</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Acta gastro-enterologica belgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MEHTA, Chinar</au><au>GUMASTE, Vivek V</au><au>LEYTIN, Anatoly</au><au>WALFISH, Aaron</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>An unusual cause of upper gastrointestinal bleeding: duodenal GIST. A case report and literature review</atitle><jtitle>Acta gastro-enterologica belgica</jtitle><addtitle>Acta Gastroenterol Belg</addtitle><date>2011-06-01</date><risdate>2011</risdate><volume>74</volume><issue>2</issue><spage>347</spage><epage>351</epage><pages>347-351</pages><issn>1784-3227</issn><abstract>A duodenal GIST is an unusual cause of upper gastrointestinal bleeding. Duodenal GISTs are rare and constitute 5% of all GISTs. A significant percentage of duodenal GISTs are located in the third and fourth portion of the duodenum and may not be detected on routine upper endoscopy. Push enteroscopy is necessary to locate these lesions. It is extremely important to differentiate a duodenal GIST from other submucosal tumors like leiomyomas, leiomyosarcomas or leiomyoblastomas which may present in a similar manner, because the treatment and prognosis differ significantly. Appropriate histological and immunohistiochemical staining is required to confirm the diagnosis. Surgical resection is the treatment of choice and may involve limited resection or a pancreaticoduodenectomy. Adjuvant therapy with Imatinib has been shown to prolong survival in patients with GIST in general.</abstract><cop>Brussels</cop><pub>Société Royale Belge de Gastro-Entérologie</pub><pmid>21861323</pmid><tpages>5</tpages></addata></record> |
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| ispartof | Acta gastro-enterologica belgica, 2011-06, Vol.74 (2), p.347-351 |
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| subjects | Adult Biological and medical sciences Diagnosis, Differential Duodenal Neoplasms - complications Duodenal Neoplasms - diagnosis Endoscopy, Gastrointestinal Female Gastroenterology. Liver. Pancreas. Abdomen Gastrointestinal Hemorrhage - diagnosis Gastrointestinal Hemorrhage - etiology Gastrointestinal Stromal Tumors - complications Gastrointestinal Stromal Tumors - diagnosis Humans Medical sciences Other diseases. Semiology Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | An unusual cause of upper gastrointestinal bleeding: duodenal GIST. A case report and literature review |
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