Short-term oxygen administration restores blunted baroreflex sensitivity in patients with type 1 diabetes

Aims/hypothesis We hypothesised that the blunted baroreflex sensitivity (BRS) typical of type 1 diabetes is caused by a higher degree of tissue hypoxia in diabetes, and tested whether oxygen increased BRS and ventilation less, equally or more than in healthy control participants (the latter suggesti...

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Veröffentlicht in:	Diabetologia 2011-08, Vol.54 (8), p.2164-2173
Hauptverfasser:	Bernardi, L., Rosengård-Bärlund, M., Sandelin, A., Mäkinen, V. P., Forsblom, C., Groop, P.-H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Baroreflex - drug effects Biological and medical sciences Blood pressure Chronic obstructive pulmonary disease Diabetes Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 1 - physiopathology Diabetes. Impaired glucose tolerance Diabetic retinopathy Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Heart rate Heart Rate - drug effects Human Physiology Humans Hyperoxia Hypotheses Hypoxia Insulin Internal Medicine Intervention Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Ophthalmology Oxygen - pharmacology Oxygen - therapeutic use Retinopathies Young Adult
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