From vice to virtue: Insights from sensitization in the nonhuman primate

Repeated, intermittent administration of psychomotor stimulants, or D1 agonists in dopamine-deficient states, induces behavioral sensitization, characterized by an enhanced response to a subsequent acute low dose challenge, which may be manifested in form of altered behavior or cognitive function. A...

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Veröffentlicht in:	Progress in neuro-psychopharmacology & biological psychiatry 2007-11, Vol.31 (8), p.1572-1592
Hauptverfasser:	Castner, Stacy A., Williams, Graham V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphetamine Animals Behavioral sensitization Central Nervous System Stimulants - pharmacology Central Nervous System Stimulants - toxicity Cognition - drug effects D1 agonist Dopamine - physiology Dopamine Agonists - pharmacology Dopamine Agonists - toxicity Humans Neural Pathways - drug effects Neural Pathways - physiology Prefrontal cortex Prefrontal Cortex - drug effects Prefrontal Cortex - physiology Primates Primates - physiology Receptors, Dopamine D1 - drug effects Working memory
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