Assessing the potency of oral polio vaccine kept outside of the cold chain during a national immunization campaign in Chad

Highlights ► we assessed the potency of mOPV3 kept at ambient temperatures during a polio vaccination campaign in Chad ► 20 vials were exposed to temperatures of up to 47.1 ∘C, and kept outside 2–8 ∘C range for up to 86.9 hours ► laboratory tests confirmed that all vials still met the potency releas...

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Veröffentlicht in:	Vaccine 2011-08, Vol.29 (34), p.5652-5656
Hauptverfasser:	Zipursky, Simona, Boualam, Liliane, Cheikh, Dah Ould, Fournier-Caruana, Jacqueline, Hamid, Djabar, Janssen, Mathias, Kartoglu, Umit, Waeterloos, Genevieve, Ronveaux, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa Allergy and Immunology Ambient temperature Applied microbiology Biological and medical sciences Campaign Chad Clinical Laboratory Techniques Cold Cold chain Controlled temperature chain (CTC) cumulative exposure Drug Storage Fundamental and applied biological sciences. Psychology Hot Temperature Human viral diseases Humans Immunization Immunization logistics Infectious diseases Laboratory tests Mass Vaccination Medical sciences Microbiology Oral polio vaccine (OPV) Polio Poliomyelitis Poliomyelitis - prevention & control Poliovirus Vaccine, Oral - immunology Refrigeration Vaccine Vaccine vial monitor (VVM) Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Viral diseases Viral diseases of the nervous system
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