Hematopoietic progenitor cells (HPCs) in node-negative invasive breast carcinomas: Immunohistochemical analysis and clinico-pathological correlations

Using immunohistochemistry, we investigated 603 negative lymph nodes from 51 patients affected by invasive breast cancer (BC) to recognize bone marrow-derived hematopoietic progenitor cells (HPCs). HPC aggregates, revealed by CD34, CD133, VEGFR1, and CD117 antisera, were determined by an intensity-d...

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Veröffentlicht in:	Pathology, research and practice research and practice, 2011-08, Vol.207 (8), p.487-491
Hauptverfasser:	Giuffrè, G., Adamo, V., Ieni, A., Colonese, F., Barresi, V., Caristi, N., Adamo, B., Tuccari, G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Breast cancer Breast Neoplasms - metabolism Breast Neoplasms - mortality Breast Neoplasms - pathology Carcinoma, Ductal, Breast - metabolism Carcinoma, Ductal, Breast - mortality Carcinoma, Ductal, Breast - pathology Female Hematopoietic Stem Cells - pathology Humans Immunohistochemistry Kaplan-Meier Estimate Ki-67 Antigen - metabolism Lymph Nodes - pathology Lymphatic Metastasis - pathology Metastasis Middle Aged Pre-metastatic niche Stem Cell Niche Stem cells
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