Formation of solid tumors by a single multinucleated cancer cell

BACKGROUND: Large multinucleated cells (MNCs) commonly exist in tumorigenic cancer cell lines that are used widely in research. However, the contributions of MNCs to tumorigenesis are unknown. METHODS: In this study, MNCs were characterized in the murine fibrosarcoma cell line UV‐2237 in vitro and i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cancer 2011-09, Vol.117 (17), p.4092-4099
Hauptverfasser:	Weihua, Zhang, Lin, Qingtang, Ramoth, Asa J., Fan, Dominic, Fidler, Isaiah J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals beta-Galactosidase - metabolism Biological and medical sciences Cancer cancer‐initiating cells Cell Line, Tumor Cellular Senescence Chemotherapy Clone Cells Fibrosarcoma Fibrosarcoma - pathology Giant Cells - pathology Leukocytes (mononuclear) Lung Neoplasms - secondary Male Medical sciences Metastases Mice Mice, Nude multinucleated cells Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Neoplasms - pathology Neoplastic Stem Cells - pathology senescent‐like cancer cells Skin Neoplasms - etiology Solid tumors Tumor cell lines Tumorigenesis Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!