A[H1N1] flu and refractory hypoxaemia: Is extracorporeal lung support the holy grail?
There is a call for methodologically robust randomised clinical trials in adult extracorporeal membrane oxygenation for its routine implementation for patients with “failing” conventional ventilation. Adherence to lung protective ventilation strategies, along with fluid balance [if required early re...
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| Veröffentlicht in: | Thorax 2011-09, Vol.66 (9), p.836-837 |
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| creator | Veenith, T V Rana, M Ercole, A Gunning, K Mahroof, R |
| description | There is a call for methodologically robust randomised clinical trials in adult extracorporeal membrane oxygenation for its routine implementation for patients with “failing” conventional ventilation. Adherence to lung protective ventilation strategies, along with fluid balance [if required early renal replacement therapy] and inotropes to support the circulation to minimise ventilator-induced lung injury, may mitigate deterioration requiring extracorporeal lung support. Currently there is no convincing evidence to routinely advocate extracorporeal lung support in failed conventional ventilation, and a prospective trial is needed to define standard best practice and to tailor extracorporeal lung support referral criteria in young patient cohort with severe refractory respiratory failure. |
| doi_str_mv | 10.1136/thoraxjnl-2011-200092 |
| format | Article |
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| subjects | Adolescent Adult Biological and medical sciences Cardiology. Vascular system Compliance Extracorporeal Membrane Oxygenation - methods Female Follow-Up Studies Hospitals Human viral diseases Humans Hypoxia - complications Hypoxia - virology Infectious diseases Influenza A Virus, H1N1 Subtype - isolation & purification Influenza, Human - complications Influenza, Human - virology Male Medical sciences Middle Aged Mortality Patients Pneumology Positive-Pressure Respiration - methods Prospective Studies Respiratory distress syndrome Respiratory Insufficiency - etiology Respiratory Insufficiency - therapy Respiratory system : syndromes and miscellaneous diseases Respiratory therapy Treatment Outcome Ventilators Viral diseases Viral diseases of the respiratory system and ent viral diseases Young Adult |
| title | A[H1N1] flu and refractory hypoxaemia: Is extracorporeal lung support the holy grail? |
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