Patch annulo-aortoplasty in an adult patient with congenital supravalvular aortic stenosis and a small aortic annulus

A 39-year-old woman with familial homozygous hypercholesterolemia had supravalvular and valvular aortic stenosis. Modified Nick’s procedure and aortic valve replacement was performed to relieve both the supravalvular and annular stenoses. At surgery, the ascending aorta was found to be narrowing at...

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Veröffentlicht in:General thoracic and cardiovascular surgery 2011-08, Vol.59 (8), p.569-571
Hauptverfasser: Morimoto, Naoto, Morimoto, Keisuke, Morimoto, Yoshihisa, Tanaka, Akiko, Sakamoto, Toshihito, Okada, Kenji, Okita, Yutaka
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container_end_page 571
container_issue 8
container_start_page 569
container_title General thoracic and cardiovascular surgery
container_volume 59
creator Morimoto, Naoto
Morimoto, Keisuke
Morimoto, Yoshihisa
Tanaka, Akiko
Sakamoto, Toshihito
Okada, Kenji
Okita, Yutaka
description A 39-year-old woman with familial homozygous hypercholesterolemia had supravalvular and valvular aortic stenosis. Modified Nick’s procedure and aortic valve replacement was performed to relieve both the supravalvular and annular stenoses. At surgery, the ascending aorta was found to be narrowing at the level of the sinotubular junction, which was compatible with congenital supravalvular aortic stenosis. Histological examination of the aortic cusps showed sclerotic change due to hypercholesterolemia. These findings indicated that familial homozygous hypercholesterolemia caused valvular aortic stenosis and exacerbated congenital supravalvular aortic stenosis.
doi_str_mv 10.1007/s11748-010-0736-2
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subjects Adult
Aortic Stenosis, Supravalvular - congenital
Aortic Stenosis, Supravalvular - diagnosis
Aortic Stenosis, Supravalvular - surgery
Aortic Valve - abnormalities
Aortic Valve - diagnostic imaging
Aortic Valve - surgery
Blood Component Removal
Cardiac Surgery
Cardiac Valve Annuloplasty
Cardiology
Case Report
Echocardiography, Transesophageal
Female
Homozygote
Humans
Hyperlipoproteinemia Type II - complications
Hyperlipoproteinemia Type II - genetics
Hyperlipoproteinemia Type II - therapy
Lipoproteins, LDL - blood
Medicine
Medicine & Public Health
Surgical Oncology
Thoracic Surgery
Tomography, X-Ray Computed
Treatment Outcome
title Patch annulo-aortoplasty in an adult patient with congenital supravalvular aortic stenosis and a small aortic annulus
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