Effects of high dose olmesartan medoxomil plus hydrochlorothiazide on blood pressure control in patients with grade 2 and grade 3 hypertension

High dose (40 mg) olmesartan medoxomil (OM) blocks the angiotensin II receptor, significantly reducing blood pressure (BP). Adding hydrochlorothiazide (HCTZ) to OM increases efficacy, but has not been evaluated in patients inadequately controlled by OM 40 mg. Patients with grade 2 and grade 3 hypert...

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Veröffentlicht in:	Journal of human hypertension 2011-09, Vol.25 (9), p.565-574
Hauptverfasser:	Rump, L C, Girerd, X, Sellin, L, Stegbauer, J
Format:	Artikel
Sprache:	eng
Schlagworte:	631/92/436/2388 692/699/75/243 692/700/565/1436/1437 Adult Aged Angiotensin Angiotensin II Antihypertensive Agents - administration & dosage Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Blood pressure Blood Pressure - drug effects Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Control Dosage and administration Double-Blind Method Drug therapy Drug Therapy, Combination Epidemiology Female Health Administration Humans Hydrochlorothiazide Hydrochlorothiazide - administration & dosage Hydrochlorothiazide - adverse effects Hypertension Hypertension - drug therapy Hypertension - physiopathology Imidazoles - administration & dosage Imidazoles - adverse effects Male Medical sciences Medicine Medicine & Public Health Middle Aged Olmesartan Medoxomil original-article Patient outcomes Patients Public Health Tetrazoles - administration & dosage Tetrazoles - adverse effects
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