Multifocal Versus Single Vision Lenses Intervention to Slow Progression of Myopia in School-age Children: A Meta-analysis

Abstract Myopia in school-aged children is a major public health problem in Asians that has been extensively studied. Multifocal lenses (MLs) are advocated as a substitute for single vision lenses (SVLs) to slow myopia progression in children, but results vary greatly across studies. We systematical...

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Veröffentlicht in:Survey of ophthalmology 2011-09, Vol.56 (5), p.451-460
Hauptverfasser: Li, Shi-Ming, MD, PhD, Ji, Ya-Zhou, MD, Wu, Shan-Shan, MD, Zhan, Si-Yan, PhD, Wang, Bo, PhD, Liu, Luo-Ru, MD, Li, Si-Yuan, MD, Wang, Ning-Li, MD, PhD, Wang, Jie Jin, MMBS, PhD
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container_end_page 460
container_issue 5
container_start_page 451
container_title Survey of ophthalmology
container_volume 56
creator Li, Shi-Ming, MD, PhD
Ji, Ya-Zhou, MD
Wu, Shan-Shan, MD
Zhan, Si-Yan, PhD
Wang, Bo, PhD
Liu, Luo-Ru, MD
Li, Si-Yuan, MD
Wang, Ning-Li, MD, PhD
Wang, Jie Jin, MMBS, PhD
description Abstract Myopia in school-aged children is a major public health problem in Asians that has been extensively studied. Multifocal lenses (MLs) are advocated as a substitute for single vision lenses (SVLs) to slow myopia progression in children, but results vary greatly across studies. We systematically searched currently available randomized controlled trials that compared the effects of MLs and SVLs in children. A meta-analysis of nine of these trials showed that MLs with powers ranging from +1.50 to +2.00D were associated with a statistically significantly decrease in myopia progression in school-aged children compared with SVLs. The benefit was greater in children with a higher level of myopia at baseline and sustained for a minimum of 24 months. Asian children appeared to have greater benefit from intervention with MLs than white children.
doi_str_mv 10.1016/j.survophthal.2011.06.002
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Multifocal lenses (MLs) are advocated as a substitute for single vision lenses (SVLs) to slow myopia progression in children, but results vary greatly across studies. We systematically searched currently available randomized controlled trials that compared the effects of MLs and SVLs in children. A meta-analysis of nine of these trials showed that MLs with powers ranging from +1.50 to +2.00D were associated with a statistically significantly decrease in myopia progression in school-aged children compared with SVLs. The benefit was greater in children with a higher level of myopia at baseline and sustained for a minimum of 24 months. 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Asian children appeared to have greater benefit from intervention with MLs than white children.</description><subject>Adolescent</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Disease Progression</subject><subject>Eyeglasses</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>meta-analysis</subject><subject>Miscellaneous</subject><subject>multifocal lenses</subject><subject>myopia</subject><subject>Myopia - physiopathology</subject><subject>Myopia - therapy</subject><subject>Ophthalmology</subject><subject>Prosthesis Design</subject><subject>Randomized Controlled Trials as Topic</subject><subject>school-aged children</subject><subject>single vision lenses</subject><subject>systematic review</subject><subject>Vision disorders</subject><subject>Vision Disorders - prevention &amp; control</subject><issn>0039-6257</issn><issn>1879-3304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkkmPEzEQRlsIxISBv4DMAXHqUF7SCwekUcQyUiKQAnO1HHd14uDYGVd3UP97OiQs4sTJkvXqK9dzZdkLDlMOvHi9m1KfjvGw7bbGTwVwPoViCiAeZBNelXUuJaiH2QRA1nkhZuVV9oRoBwBK1uXj7Erwikuuikk2LHvfuTZa49kdJuqJrVzYeGR3jlwMbIGBkNht6DAdMXSnuy6ylY_f2ecUNwnpJxdbthziwRnmAlvZbYw-Nxtk863zTcLwht2wJXYmN8H4gRw9zR61xhM-u5zX2df3777MP-aLTx9u5zeL3KqCd_kaSmhag-taNaJo5awCIytlsVESLcyw5LMShaiMaHgNbdWWDW9NKawCge1MXmevzrmHFO97pE7vHVn03gSMPemqUlwoKcuRrM-kTZEoYasPye1NGjQHfRKvd_ov8fokXkOhR_Fj7fNLl369x-Z35S_TI_DyAhgaZbfJBOvoD6dUUZXAR25-5nB0cnSYNFmHYZzXJbSdbqL7r-e8_SfFehfc2PgbDki72KfxG0hzTUKDXp025bQonMOYUgr5A8JHvg4</recordid><startdate>20110901</startdate><enddate>20110901</enddate><creator>Li, Shi-Ming, MD, PhD</creator><creator>Ji, Ya-Zhou, MD</creator><creator>Wu, Shan-Shan, MD</creator><creator>Zhan, Si-Yan, PhD</creator><creator>Wang, Bo, PhD</creator><creator>Liu, Luo-Ru, MD</creator><creator>Li, Si-Yuan, MD</creator><creator>Wang, Ning-Li, MD, PhD</creator><creator>Wang, Jie Jin, MMBS, PhD</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20110901</creationdate><title>Multifocal Versus Single Vision Lenses Intervention to Slow Progression of Myopia in School-age Children: A Meta-analysis</title><author>Li, Shi-Ming, MD, PhD ; Ji, Ya-Zhou, MD ; Wu, Shan-Shan, MD ; Zhan, Si-Yan, PhD ; Wang, Bo, PhD ; Liu, Luo-Ru, MD ; Li, Si-Yuan, MD ; Wang, Ning-Li, MD, PhD ; Wang, Jie Jin, MMBS, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-b070dfaeb94d26f3580a384ced43ec05e7157e228a2d190f8f7d1fa72c402ef53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adolescent</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Disease Progression</topic><topic>Eyeglasses</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>meta-analysis</topic><topic>Miscellaneous</topic><topic>multifocal lenses</topic><topic>myopia</topic><topic>Myopia - physiopathology</topic><topic>Myopia - therapy</topic><topic>Ophthalmology</topic><topic>Prosthesis Design</topic><topic>Randomized Controlled Trials as Topic</topic><topic>school-aged children</topic><topic>single vision lenses</topic><topic>systematic review</topic><topic>Vision disorders</topic><topic>Vision Disorders - prevention &amp; 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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Adolescent
Biological and medical sciences
Child
Disease Progression
Eyeglasses
Humans
Medical sciences
meta-analysis
Miscellaneous
multifocal lenses
myopia
Myopia - physiopathology
Myopia - therapy
Ophthalmology
Prosthesis Design
Randomized Controlled Trials as Topic
school-aged children
single vision lenses
systematic review
Vision disorders
Vision Disorders - prevention & control
title Multifocal Versus Single Vision Lenses Intervention to Slow Progression of Myopia in School-age Children: A Meta-analysis
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