Atorvastatin induced increase in homologous angiotensin I converting enzyme (ACE2) mRNA is associated to decreased fibrosis and decreased left ventricular hypertrophy in a rat model of diabetic cardiomyopathy

This study has investigated the effect of atorvastatin on the progression of cardiac remodelling and ACE- 2 expression in diabetic myocardium in rats. Diabetes was induced in Holtzman rats with an intraperitoneal injection of streptozotocin. The animals were divided into 3 groups: (1) normal control...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Revista peruana de medicina experimental y salud pública 2011-06, Vol.28 (2), p.264-272
Hauptverfasser:	Aguilar, Cristian, Ventura, Freddy, Rodríguez-Delfín, Luis
Format:	Artikel
Sprache:	eng ; spa
Schlagworte:	Animals Atorvastatin Calcium Diabetic Cardiomyopathies - genetics Diabetic Cardiomyopathies - prevention & control Disease Models, Animal Fibrosis - genetics Fibrosis - prevention & control Heptanoic Acids - therapeutic use Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hypertrophy, Left Ventricular - genetics Male Peptidyl-Dipeptidase A - genetics Pyrroles - therapeutic use Rats Rats, Sprague-Dawley RNA, Messenger - biosynthesis RNA, Messenger - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!