Development and validation of I-DNA1: a 15-Loci multiplex system for identity testing
This paper presents a system for the multiplex amplification of 15 loci, known as I-DNA1, which combines mini and midiSTR technology, with amplicon sizes ranging from 49 to 297 bp. I-DNA1 analyses all the STR loci included in the CODIS and the Interpol Standard Set of loci, nine of the ten European...
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| Veröffentlicht in: | International journal of legal medicine 2011-09, Vol.125 (5), p.685-694 |
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| container_title | International journal of legal medicine |
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| creator | Odriozola, A. Aznar, J. M. Celorrio, D. Bravo, M. L. Builes, J. J. Val-Bernal, J. F. de Pancorbo, Marian M. |
| description | This paper presents a system for the multiplex amplification of 15 loci, known as I-DNA1, which combines mini and midiSTR technology, with amplicon sizes ranging from 49 to 297 bp. I-DNA1 analyses all the STR loci included in the CODIS and the Interpol Standard Set of loci, nine of the ten European core loci and seven of the eight German core loci, making it suitable for use in identifying humans. Moreover, its high sensitivity and the small size of its amplicons mean that I-DNA1 is potentially highly useful for analysing highly degraded and/or very small DNA samples. |
| doi_str_mv | 10.1007/s00414-010-0539-0 |
| format | Article |
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M. ; Celorrio, D. ; Bravo, M. L. ; Builes, J. J. ; Val-Bernal, J. F. ; de Pancorbo, Marian M.</creator><creatorcontrib>Odriozola, A. ; Aznar, J. M. ; Celorrio, D. ; Bravo, M. L. ; Builes, J. J. ; Val-Bernal, J. F. ; de Pancorbo, Marian M.</creatorcontrib><description>This paper presents a system for the multiplex amplification of 15 loci, known as I-DNA1, which combines mini and midiSTR technology, with amplicon sizes ranging from 49 to 297 bp. I-DNA1 analyses all the STR loci included in the CODIS and the Interpol Standard Set of loci, nine of the ten European core loci and seven of the eight German core loci, making it suitable for use in identifying humans. Moreover, its high sensitivity and the small size of its amplicons mean that I-DNA1 is potentially highly useful for analysing highly degraded and/or very small DNA samples.</description><identifier>ISSN: 0937-9827</identifier><identifier>EISSN: 1437-1596</identifier><identifier>DOI: 10.1007/s00414-010-0539-0</identifier><identifier>PMID: 21258942</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject><![CDATA[Autopsies ; DNA Fingerprinting - legislation & jurisprudence ; DNA Fingerprinting - methods ; DNA Fingerprinting - statistics & numerical data ; Female ; Forensic Anthropology - legislation & jurisprudence ; Forensic Anthropology - methods ; Forensic Medicine ; Gene Frequency - genetics ; Genetic Loci - genetics ; Genetic testing ; Humans ; Liver - pathology ; Male ; Medical Law ; Medicine ; Medicine & Public Health ; Microsatellite Repeats - genetics ; Multiplex Polymerase Chain Reaction - methods ; Multiplex Polymerase Chain Reaction - statistics & numerical data ; Myocardium - pathology ; Original Article ; Postmortem Changes ; Reagent Kits, Diagnostic - statistics & numerical data ; Reproducibility of Results ; Spain]]></subject><ispartof>International journal of legal medicine, 2011-09, Vol.125 (5), p.685-694</ispartof><rights>Springer-Verlag 2011</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-df6283a260221fb834688738ac290652446177009a8efcffd2b8b4a3aad05f2a3</citedby><cites>FETCH-LOGICAL-c403t-df6283a260221fb834688738ac290652446177009a8efcffd2b8b4a3aad05f2a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00414-010-0539-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00414-010-0539-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21258942$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Odriozola, A.</creatorcontrib><creatorcontrib>Aznar, J. M.</creatorcontrib><creatorcontrib>Celorrio, D.</creatorcontrib><creatorcontrib>Bravo, M. L.</creatorcontrib><creatorcontrib>Builes, J. J.</creatorcontrib><creatorcontrib>Val-Bernal, J. F.</creatorcontrib><creatorcontrib>de Pancorbo, Marian M.</creatorcontrib><title>Development and validation of I-DNA1: a 15-Loci multiplex system for identity testing</title><title>International journal of legal medicine</title><addtitle>Int J Legal Med</addtitle><addtitle>Int J Legal Med</addtitle><description>This paper presents a system for the multiplex amplification of 15 loci, known as I-DNA1, which combines mini and midiSTR technology, with amplicon sizes ranging from 49 to 297 bp. I-DNA1 analyses all the STR loci included in the CODIS and the Interpol Standard Set of loci, nine of the ten European core loci and seven of the eight German core loci, making it suitable for use in identifying humans. 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| ispartof | International journal of legal medicine, 2011-09, Vol.125 (5), p.685-694 |
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| source | MEDLINE; SpringerLink Journals; HeinOnline Law Journal Library |
| subjects | Autopsies DNA Fingerprinting - legislation & jurisprudence DNA Fingerprinting - methods DNA Fingerprinting - statistics & numerical data Female Forensic Anthropology - legislation & jurisprudence Forensic Anthropology - methods Forensic Medicine Gene Frequency - genetics Genetic Loci - genetics Genetic testing Humans Liver - pathology Male Medical Law Medicine Medicine & Public Health Microsatellite Repeats - genetics Multiplex Polymerase Chain Reaction - methods Multiplex Polymerase Chain Reaction - statistics & numerical data Myocardium - pathology Original Article Postmortem Changes Reagent Kits, Diagnostic - statistics & numerical data Reproducibility of Results Spain |
| title | Development and validation of I-DNA1: a 15-Loci multiplex system for identity testing |
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